Results 71 to 80 of about 5,329,875 (275)

Evaluating the Utility of Paired Tumor and Germline Targeted DNA Sequencing for Pediatric Oncology Patients: A Single Institution Report

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Objective To evaluate the diagnostic yield and utility of universal paired tumor–normal multigene panel sequencing in newly diagnosed pediatric solid and central nervous system (CNS) tumor patients and to compare the detection of germline pathogenic/likely pathogenic variants (PV/LPVs) against established clinical referral criteria for cancer ...
Natalie Waligorski   +9 more
wiley   +1 more source

Variance Allocation and Shapley Value

open access: yes, 2017
Motivated by the problem of utility allocation in a portfolio under a Markowitz mean-variance choice paradigm, we propose an allocation criterion for the variance of the sum of $n$ possibly dependent random variables.
Colini-Baldeschi, Riccardo   +2 more
core   +1 more source

Reducing variance in univariate smoothing

open access: yes, 2007
A variance reduction technique in nonparametric smoothing is proposed: at each point of estimation, form a linear combination of a preliminary estimator evaluated at nearby points with the coefficients specified so that the asymptotic bias remains ...
Cheng, Ming-Yen   +2 more
core   +2 more sources

Zoomorphic variation with copulation duration in Centrobolus [PDF]

open access: yesArthropods, 2020
Centrobolus typically has prolonged copulation as a form of syn-copula mateguarding. Variations in the copulation duration were calculated and analysed in four species of the millipede genus Centrobolus.
Mark Cooper
doaj  

Describing posterior distributions of variance components: Problems and the use of null distributions to aid interpretation

open access: yesMethods in Ecology and Evolution, 2023
Assessing the biological relevance of variance components estimated using Markov chain Monte Carlo (MCMC)‐based mixed‐effects models is not straightforward.
Joel L. Pick   +10 more
doaj   +1 more source

Intravitreal GD2‐Specific Chimeric Antigen Receptor T‐Cell Therapy for Refractory Retinoblastoma

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Effective treatments for advanced, treatment‐resistant retinoblastoma (RB) remain limited. GD2‐specific chimeric antigen receptor (CAR) T cells show potent antitumor activity with minimal toxicity but have not previously been evaluated in RB.
Subongkoch Subhadhirasakul   +13 more
wiley   +1 more source

The Mean and Variance of the Mean‐Variance Decision Rule [PDF]

open access: yesAmerican Journal of Agricultural Economics, 1990
AbstractThe widely used mean‐variance approach to decisions under uncertainty requires estimates of the parameters of the joint distribution of returns. When optimal behavior is determined using estimates, rather than the true values, the decision is a random variable.
James A. Chalfant   +2 more
openaire   +2 more sources

ESTIMATION OF SAMPLE SPACING IN STOCHASTIC PROCESSES

open access: yesImage Analysis and Stereology, 2017
Motivated by applications in electron microscopy, we study the situation where a stationary and isotropic random field is observed on two parallel planes with unknown distance. We propose an estimator for this distance.
Anders Rønn-Nielsen   +2 more
doaj   +1 more source

Outcomes of Live Virus Vaccination in Patients With Vascular Anomalies Being Treated With Sirolimus

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Live vaccination in patients with vascular anomalies (VA) receiving sirolimus remains controversial due to immunosuppressive effects and theoretical risks. Procedure This single‐center retrospective study included patients with VA less than 4 years old at the start of sirolimus therapy who were incompletely vaccinated.
Svatava Merkle   +5 more
wiley   +1 more source

Characteristics and Properties of a Simple Linear Regression Model

open access: yesFolia Oeconomica Stetinensia, 2016
A simple linear regression model is one of the pillars of classic econometrics. Despite the passage of time, it continues to raise interest both from the theoretical side as well as from the application side.
Kowal Robert
doaj   +1 more source

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