Results 131 to 140 of about 2,181,553 (341)

Which method is optimal for estimating variance components and their variability in generalizability theory? evidence form a set of unified rules for bootstrap method. [PDF]

PLoS One, 2023
Li G.
europepmc   +1 more source

Elements of a Theory of Design Limits to Optimal Policy [PDF]

This paper presents a framework for understanding the limits that exist in optimal policy design in dynamic contexts. We consider the design of policies in the context of dynamic linear models.
Steven N. Durlauf, William A. Brock
core  

Peptide‐based ligand antagonists block a Vibrio cholerae adhesin

FEBS Letters, EarlyView.
The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang, Grace Du, Charity Yongo‐Luwawa, Angelina Lu, Brett Kinrade, Kim Munro, Karl E. Klose, William D. Lubell, Peter Davies, Shuaiqi Guo   +9 more
wiley   +1 more source

Heritability and variance components of seed size in wild species: influences of breeding design and the number of genotypes tested. [PDF]

Heredity (Edinb), 2023
Larios E, Ramirez-Parada TH, Mazer SJ.
europepmc   +1 more source

VARIANCE OF PHRASEOLOGICAL UNITS WITH THE VERBAL COMPONENT IN THE ADYGHE LANGUAGE

, 2019
Goshsim Turkubievna Tuguz
openalex   +1 more source

Efficient Estimation of an Additive Quantile Regression Model [PDF]

In this paper two kernel-based nonparametric estimators are proposed for estimating the components of an additive quantile regression model. The first estimator is a computationally convenient approach which can be viewed as a viable alternative to the ...
Cheng, Yebin, De Gooijer, Jan, Zerom, Dawit   +2 more
core   +1 more source

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

FEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source

Avaliação genética do crescimento de bovinos Nelore Mocho, por meio de modelos de multicaracterísticas

Revista Ceres
RESUMO Objetivou-se, com este trabalho, estimar parâmetros genéticos para características do crescimento de animais da raça Nelore Mocho. Foram utilizados pesos corporais (Kg) ajustados aos 205 (P205), 365 (P365) e 550 (P550) dias.
Isabella Coutinho de Barros, Rodrigo Reis Mota, Luciano Pinheiro da Silva, Paulo Luiz Souza Carneiro, Raimundo Martins Filho, Carlos Henrique Mendes Malhado   +5 more
doaj   +1 more source

REHE: Fast variance components estimation for linear mixed models. [PDF]

Genet Epidemiol, 2021
Yue K, Ma J, Thornton T, Shojaie A.
europepmc   +1 more source

Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer

FEBS Letters, EarlyView.
Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani, Noemi E. Nwosu, Viktoria Gocke, Müge Kasanmascheff, Hannes Mutschler   +4 more
wiley   +1 more source