Results 131 to 140 of about 7,497,770 (317)

Disruption of SETD3‐mediated histidine‐73 methylation by the BWCFF‐associated β‐actin G74S mutation

open access: yesFEBS Letters, EarlyView.
The β‐actin G74S mutation causes altered interaction of actin with SETD3, reducing histidine‐73 methylation efficiency and forming two distinct actin variants. The variable ratio of these variants across cell types and developmental stages contributes to tissue‐specific phenotypical changes. This imbalance may impair actin dynamics and mechanosensitive
Anja Marquardt   +8 more
wiley   +1 more source

Robust Henderson III estimators of variance components in the nested error model [PDF]

open access: yes
Common methods for estimating variance components in Linear Mixed Models include Maximum Likelihood (ML) and Restricted Maximum Likelihood (REML). These methods are based on the strong assumption of multivariate normal distribution and it is well know ...
Betsabé Pérez   +2 more
core  

Purification tags markedly affect self‐aggregation of CPEB3

open access: yesFEBS Letters, EarlyView.
Although recombinant proteins are used to study protein aggregation in vitro, uncleaved tags can interfere with accurate interpretation. Our findings demonstrate that His₆‐GFP and His₁₂ tags significantly affect liquid droplet and amyloid fibril formation in the intrinsically disordered region (IDR) of mouse cytoplasmic polyadenylation element‐binding ...
Harunobu Saito   +6 more
wiley   +1 more source

Numerical least-square method for resolving complex pulse height spectra [PDF]

open access: yes, 1967
Linear least-square method resolves complex pulse height spectra, allowing for calculation of relative intensity, of statistical variance based on counting statistics of the correlation between library components, and of the goodness-of-fit chi square ...
Schmadebeck, R., Trombka, J. I.
core   +1 more source

Circulating histones as clinical biomarkers in critically ill conditions

open access: yesFEBS Letters, EarlyView.
Circulating histones are emerging as promising biomarkers in critical illness due to their diagnostic, prognostic, and therapeutic potential. Detection methods such as ELISA and mass spectrometry provide reliable approaches for quantifying histone levels in plasma samples.
José Luis García‐Gimenez   +17 more
wiley   +1 more source

Dissecting total genetic variance into additive and dominance components of purebred and crossbred pig traits

open access: yesAnimal, 2019
The partition of the total genetic variance into its additive and non-additive components can differ from trait to trait, and between purebred and crossbred populations.
L. Tusell   +5 more
doaj  

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