Results 71 to 80 of about 415,967 (312)
Diversity and complexity in neural organoids
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Noise variance estimation based on image segmentation
A new two-step noise variance estimation algorithm was proposed based on image segmentation. In the first step, a noisy image was smoothed and was segmented by the statistical region merge (SRM) algorithm, then the variance of each region was computed ...
WANG Zhi-ming
doaj +1 more source
The human gut microbiome across the life course
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero +4 more
wiley +1 more source
Semi-bayesian D-optimal designs and estimation procedures for mean and variance functions. [PDF]
Semi-Bayesian D-optimal designs for fitting mean and variance functions are derived for some prior distributions on the variance function parameters. The impact of the mean of the prior and of the uncertainty about this mean is analyzed.
Goos, Peter, Vandebroek, Martina
core
This article presents an improved class of efficient estimators aimed at estimating the finite population variance of the study variable. These estimators are especially useful when we have information about the minimum/maximum values of the auxiliary ...
Umer Daraz, Jinbiao Wu, Olayan Albalawi
doaj +1 more source
A Bayesian “Sandwich” for Variance Estimation
11 pages, 2 ...
Li, Kendrick, Rice, Kenneth
openaire +3 more sources
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
Further Bounds for the Estimation Error Variance of a Continuous Stream with Stationary Variogram
In this paper we establish an upper bound for the estimation error variance of a continuous stream with a stationary variogram V which is assumed to be of r-Hölder type (Lipschitzian) on [-d, d]
Dragomir, Sever S +2 more
core
Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas +6 more
wiley +1 more source
Negative variance estimates in panel data models [PDF]
Negative values for estimated variances can arise in a panel data context. Empirical and theoretical literature dismisses the problem as not serious and a practical solution is to replace negative variances by its boundary value, i.e. zero. While this is
Laura Magazzini, Giorgio Calzolari
core

