Results 81 to 90 of about 415,967 (312)
FEBS Letters, EarlyView.An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley +1 more source
StatsIn repeated-measures meta-analyses, raw data are often unavailable, preventing the calculation of the correlation coefficient r between pre- and post-intervention values.
Vasileios Papadopoulos
doaj +1 more source
Electron transfer between complexes III and IV in S. cerevisiae mitochondrial membranes
FEBS Letters, EarlyView.Mitochondrial oxidative phosphorylation in S. cerevisiae mitoplasts is limited by complex IV catalytic capacity, rather than two‐dimensional cytochrome c diffusion. At physiological cytochrome c : supercomplex ratios at salinity equivalent to that of 20 mm monovalent salt, activity is maximized, indicating that this low ionic strength accurately mimics
Ana Paula Lobez +2 more
wiley +1 more source
Improved Coefficient and Variance Estimation in Stable First-Order Dynamic Regression Models [PDF]
In dynamic regression models the least-squares coefficient estimators are biased in finite samples, and so are the usual estimators for the disturbance variance and for the variance of the coefficient estimators.
Garry D. A. Phillips, Jan F. Kiviet
core
FEBS Letters, EarlyView.Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley +1 more source
A Note on Bounds for the Estimation Error Variance of a Continuous Stream With Stationary Variogram
, 1998 In this paper, by the use of an Ostrowski type integral inequality for double integrals, we establish an upper bound for the estimation error variance of a continuous stream with stationary ...
Dragomir, Sever S, Barnett, Neil S
core
Improved heritability estimation from genome-wide SNPs
, 2012 Narrow-sense heritability (h(2)) is an important genetic parameter that quantifies the proportion of phenotypic variance in a trait attributable to the additive genetic variation generated by all causal variants.
Johnson, Michael R. +7 more
core +1 more source
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
FEBS Letters, EarlyView.Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
A Class of Estimators for Estimating the Variance of the Ratio Estimator
JOURNAL OF THE JAPAN STATISTICAL SOCIETY, 2004 Summary: We have proposed a class of estimators for the variance of the ratio estimator which includes two standard estimators \(V_0\), \(V_2\) and the estimators \(V_H\) and \(V_3\) suggested by \textit{R. M. Royall} and \textit{K. R. Eberhardt} [Sankya, Ser. C 37, 43--52 (1975; Zbl 0335.62007)] and \textit{C. F.
Upadhyaya, Lakshmi N. +2 more
openaire +3 more sources
The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
Molecular Oncology, EarlyView.The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
wiley +1 more source