Results 101 to 110 of about 1,198,252 (292)

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

Impaired Discriminative Function in Patients with Chronic Pain Measured by Variance in Straight Leg Raising

open access: yesPain Research and Management, 1996
Many chronic pain patients seem to have difficulty regulating exercise programs and require detailed, precise instructions of what exercises to do as well as their frequency and timing. This may be due to a lack of information concerning the state of the
Ann Marie Hoirch   +4 more
doaj   +1 more source

An intracellular transporter mitigates the CO2‐induced decline in iron content in Arabidopsis shoots

open access: yesFEBS Letters, EarlyView.
This study identifies a gene encoding a transmembrane protein, MIC, which contributes to the reduction of shoot Fe content observed in plants under elevated CO2. MIC is a putative Fe transporter localized to the Golgi and endosomal compartments. Its post‐translational regulation in roots may represent a potential target for improving plant nutrition ...
Timothy Mozzanino   +7 more
wiley   +1 more source

Interpreting adjoint and ensemble sensitivity toward the development of optimal observation targeting strategies

open access: yesMeteorologische Zeitschrift, 2007
Two general methods, adjoint or singular vector methods, and ensemble-based methods, have been previously investigated to identify locations where observations would have a significant positive impact on a numerical weather model forecast. In this paper,
Brian C. Ancell, Gregory J. Hakim
doaj   +1 more source

A Cre‐dependent lentiviral vector for neuron subtype‐specific expression of large proteins

open access: yesFEBS Letters, EarlyView.
We designed a versatile and modular lentivector comprising a Cre‐dependent switch and self‐cleaving 2A peptide and tested it for co‐expression of GFP and a 2.8 kb gene of interest (GOI) in mouse cortical parvalbumin (PV+) interneurons and midbrain dopamine (TH+) neurons.
Weixuan Xue   +6 more
wiley   +1 more source

Combing Instrumental Variable and Variance Matching for Aircraft Flutter Model Parameters Identification

open access: yesShock and Vibration, 2019
When the observed input-output data are corrupted by the observed noises in the aircraft flutter stochastic model, we need to obtain the more exact aircraft flutter model parameters to predict the flutter boundary accuracy and assure flight safety.
Hong Jianwang   +2 more
doaj   +1 more source

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