Results 91 to 100 of about 1,548,550 (297)

ipdgc/GP2-visualise-longitudinal-variant-effects: GP2 Hackathon Visualise Longitudinal variant Effects

, 2022
Code associated with Project 9: Visualize longitudinal and cross-sectional variant effects from the 2021 GP2/IPDGC Hackathon and manuscript "The IPDGC/GP2 Hackathon - an open science event for training in data science, genomics, and collaboration using ...
NikitaSPillay, Regina Hertfelder Reynolds   +1 more
core   +1 more source

Serum Myonectin Levels Are Positively Associated With Physical Function and Lower Frailty‐Related Limitation in Maintenance Hemodialysis Patients: A Cross‐Sectional Study

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Maintenance hemodialysis (MHD) patients frequently suffer from frailty, characterized by reduced physical function and poor prognosis. Myokines, such as myonectin, secreted by muscle, are emerging regulators of systemic health. This study investigated the relationship between serum myonectin, adipokines (adiponectin, omentin), and ...
Kenichi Kono, Yoshifumi Moriyama, Koji Ohashi, Naoya Otaka, Minako Tatsumi, Toyoaki Murohara, Noriyuki Ouchi, Satoru Oshima   +7 more
wiley   +1 more source

Comparative Evaluation of Hemodiafiltration, Hemoperfusion, and Standard Hemodialysis on Efficacy, Inflammatory Control, Dialysis Adequacy, and Safety in End‐Stage Renal Disease: A Prospective Observational Study

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Chronic micro‐inflammation in patients with end‐stage renal disease (ESRD) is a significant driver of cardiovascular complications and diminished quality of life. While standard hemodialysis (SHD) effectively manages small‐molecule clearance, its ability to remove medium‐to‐large uremic toxins—the primary catalysts of systemic ...
Hongwei Zuo, Weisi Dai, Jie Mao, Mei Ye, Xingshan Lu, Xiaocui Zhang   +5 more
wiley   +1 more source

Safety of Daprodustat for the Treatment of Chronic Kidney Disease Anemia: Final Analysis of a Multicenter Postmarketing Surveillance Study in Japan

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction This final analysis of a multicenter, prospective postmarketing surveillance study evaluated the safety of daprodustat in patients with chronic kidney disease anemia in routine clinical practice in Japan. Methods Patients who initiated daprodustat between September 2020 and July 2022 were registered.
Tadao Akizawa, Kyomi Kanaya, Kiyomi Aizawa, Masanori Onoki, Hirofumi Ozeki, Kazuko Suzuki, Ai Hayashi, Tomohiko Asamura   +7 more
wiley   +1 more source

Microstructure Evolution of Cold-Rolled Carbide-Free Bainite Steel Sheets During Continuous Annealing Process

Metals
A modified carbide-free bainite (CFB) steel has been developed, building on existing alloys for compatibility with commercial continuous annealing lines (CALs), featuring a low austenitization temperature and short overaging time.
Bahareh Mobedpour, Fateh Fazeli, Hatem Zurob   +2 more
doaj   +1 more source

The methylenetetrahydrofolate reductase gene variant C677T influences susceptibility to migraine with aura

BMC Medicine, 2004
Background The C677T variant in the methylenetetrahydrofolate reductase (MTHFR) gene is associated with increased levels of circulating homocysteine and is a mild risk factor for vascular disease.
Sundholm James, Ovcaric Micky, Lea Rod A, MacMillan John, Griffiths Lyn R   +4 more
doaj   +1 more source

Variant-level quality metrics of high-quality variants in the BP dataset processed by different methods.

, 2019
Variant-level quality metrics of high-quality variants in the BP dataset processed by different methods.
Jiajin Li (457126), Sungoo Hwang (8150112), Brandon Jew (8124671), Giovanni Coppola (46572), Jae Hoon Sul (8124677), Nelson B. Freimer (8150115), Lingyu Zhan (8150109)   +6 more
core   +1 more source

Forecasting the Dialysis Burden in Japan: Validation‐Based Projections of Prevalence and Incidence Through 2050

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Japan has one of the highest dialysis prevalence rates worldwide and a shrinking, aging population. Whether dialysis burden has entered a sustained post‐peak phase or whether recent declines partly reflect pandemic‐related disruptions remains uncertain.
Hatice Şahin, Berrak Itır Aylı, Nüket Paksoy   +2 more
wiley   +1 more source

Surveillance for Chlamydia trachomatis variants escaping detection with the Aptima Combo 2 assay in Canada from 2019 to 2021

Microbiology Spectrum
Nucleic acid amplification tests (NAATs) are the method of choice for Chlamydia trachomatis diagnosis, but these strategies are susceptible to target site mutations. C.
Felicia Roy, Jennifer Beirnes, Jason J. LeBlanc, Suzanne Gibbons, Aida Sivro, Alberto Severini   +5 more
doaj   +1 more source

Association Between Individualized Education for Kidney Replacement Therapy Modality Selection and Peritoneal Dialysis Initiation: A Cross‐Sectional Study

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction Peritoneal dialysis (PD) is an established home‐based kidney replacement therapy (KRT), but its uptake remains low in Japan. We evaluated whether individualized education in a dedicated outpatient clinic was associated with the initiation of PD.
Yasuko Ito, Ryuichi Yoshimura, Takaki Yamauchi, Yuta Funakoshi, Hirotaka Sonoda, Seiji Kobayashi, Hiroyuki Terawaki, Takafumi Ito   +7 more
wiley   +1 more source