Results 71 to 80 of about 2,797,849 (300)

Accelerated Current Decay Kinetics of a Rare Human Acid-Sensing ion Channel 1a Variant That Is Used in Many Studies as Wild Type

Frontiers in Molecular Neuroscience, 2019
Acid-sensing ion channels (ASICs) are neuronal Na+-permeable ion channels that are activated by extracellular acidification and are involved in fear sensing, learning, neurodegeneration after ischemia, and in pain sensation.
Anand Vaithia, Sabrina Vullo, Zhong Peng, Omar Alijevic, Stephan Kellenberger   +4 more
doaj   +1 more source

Pediatric Oncology Nursing Competencies in Latin America and the Caribbean: A Scoping Review to Inform Practice, Education, and Research

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Nurses are central to cancer care for children and adolescents, yet no comprehensive synthesis has defined essential core competencies for pediatric oncology nursing (PON) practice internationally, particularly in Latin America and the Caribbean (LAC).
Luís Carlos Lopes‐Júnior, Edmara Bazoni Soares Maia, Soad Fuentes‐Alabí, Courtney E. Sullivan, Monnie Abraham, Mauricio Maza, Liliana Vásquez Ponce, Regina Aparecida Garcia Lima   +7 more
wiley   +1 more source

Classification of iPSC-derived cultures using convolutional neural networks to identify single differentiated neurons for isolation or measurement

Discover Artificial Intelligence
Understanding neurodegenerative disease pathology requires a close examination of neurons and their processes. However, image-based single-cell analyses of neurons often require laborious and time-consuming manual classification tasks. Here, we present a
Purva Patel, Lina K. Mohammed Ali, Uma Kaushik, Mallory Wright, Kaylee Green, Jason E. Waligorski, Colin L. Kremitzki, Graham W. Bachman, Serena N. Elia, William J. Buchser   +9 more
doaj   +1 more source

Diffuse sclerosing variant of thyroid carcinoma presenting as Hashimoto thyroiditis: a case report [Difuzno sklerozirajući oblik papilarnog karcinoma štitnjače nalik Hashimoto tireoiditisu: prikaz slučaja] [PDF]

, 2012
The aim of report is to present a case of a rare diffuse sclerosing variant of a papillary thyroid carcinoma. A 15-year old girl referred for ultrasound examination because of painless thyroid swelling lasting 10 days before.
Banek, Tomislav, Kusačić Kuna, Sanja, Prgomet, Drago, Trutin Ostović, Karmen, Vukasović, Anamarija   +4 more
core  

Variant Supercurrents and Linearized Supergravity

, 2011
In this paper the variant supercurrents based on consistency and completion in off-shell N=1 supergravity are studied. We formulate the embedding relations for supersymmetric current and energy tensor into supercurrent multiplet. Corresponding linearized
Gates S J, Jia-Hui Huang, Komargodski Z, Ogievetsky V, Ogievetsky V, Sibo Zheng, Siegel W, Weinberg S, Wess J, Yonekura K   +9 more
core   +1 more source

A novel ZRS variant causes preaxial polydactyly type I by increased sonic hedgehog expression in the developing limb bud. [PDF]

, 2020
PurposePreaxial polydactyly (PPD) is a common congenital hand malformation classified into four subtypes (PPD I-IV). Variants in the zone of polarizing activity regulatory sequence (ZRS) within intron 5 of the LMBR1 gene are linked to most PPD types ...
Ahituv, Nadav, Chen, Tao, Gao, Bo, Li, Quan-Zhen, Li, Yongyong, Lian, Chengjie, Liao, Zhiheng, Malik, Sajid, Mohan, Chandra, Sharma, Swarkar, Su, Deying, Su, Peiqiang, Wang, Tingting, Xing, Chao, Xu, Caixia, Yan, Mei, Yang, Xiaoming, Zhong, Dongmei, Zhou, Hang, Zhou, Taifeng   +19 more
core  

NRASQ61R Expression in Lymphatic Endothelial Cells Causes Enlarged Vessels, Hemorrhagic Chylous Effusions, and High Mortality in a Mouse Model of Kaposiform Lymphangiomatosis

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Kaposiform lymphangiomatosis (KLA) is an aggressive complex lymphatic anomaly. Patients exhibit malformed lymphatic vessels and often develop hemorrhagic effusions and elevated angiopoietin‐2 (Ang‐2) levels. A somatic NRAS p.Q61R (NRASQ61R) mutation has been associated with KLA.
C. Griffin McDaniel, Patricia Pastura, Joshua P. Scallan, Timothy D. Le Cras   +3 more
wiley   +1 more source

Comprehensive Genome Analysis of 6,000 USA SARS-CoV-2 Isolates Reveals Haplotype Signatures and Localized Transmission Patterns by State and by Country

Frontiers in Microbiology, 2020
Genomic analysis of SARS-CoV-2 sequences is crucial in determining the effectiveness of prudent safer at home measures in the United States (US). By haplotype analysis of 6,356 US isolates, we identified a pattern of strongly localized outbreaks at the ...
Lishuang Shen, Jennifer Dien Bard, Jennifer Dien Bard, Jaclyn A. Biegel, Jaclyn A. Biegel, Alexander R. Judkins, Alexander R. Judkins, Xiaowu Gai, Xiaowu Gai   +8 more
doaj   +1 more source

Pulmonary Dysfunction Is Associated With Sleep Study Abnormalities in Children With Sickle Cell Disease: A Multicenter Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Introduction Pulmonary dysfunction and sleep abnormalities are common in children with sickle cell disease (SCD) and are associated with worse clinical outcomes. Whether spirometry abnormalities are associated with polysomnography (PSG) findings remains unclear.
Ammar Saadoon Alishlash, Anis Rabbani Nourani, A. K. M. Fazlur Rahman, Dima Ezmigna, Tarig Ali‐Dinar   +4 more
wiley   +1 more source

A High‐Sensitivity Circulating Nucleic Acid Sequencing Assay for Assessing Treatment Response to Alectinib in a Pediatric Patient With ALK‐Rearranged Non–Small Cell Lung Cancer

Pediatric Blood &Cancer, EarlyView.
Alberto D. Guerra, Nicholas F. Evageliou, Vandana Batra, Kristen L. Dalton, Stephanie Ortel, Usman Ashraf, Tricia R. Bhatti, Lisa J. States, Lea F. Surrey, Theodore W. Laetsch   +9 more
wiley   +1 more source