Results 51 to 60 of about 2,797,849 (300)

The cis-Regulatory Element of SNCA Intron 4 Modulates Susceptibility to Parkinson’s Disease in Han Chinese

Frontiers in Genetics, 2020
Objective: A novel functional cis-regulatory element (CRE) located at SNCA intron 4 has recently been identified in association with Parkinson’s disease (PD) risk in European descendants.
Shi-Guo Zhu, Shi-Guo Zhu, Hui Lu, Miao Mao, Zhao-Feng Li, Lei Cui, Begench Ovlyakulov, Xiong Zhang, Jian-Hong Zhu, Jian-Hong Zhu   +9 more
doaj   +1 more source

Survival Outcomes and Complications Among Canadian Children With Retinoblastoma: A Population‐Based Report From CYP‐C

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Purpose Retinoblastoma (RB) is the most common pediatric ocular cancer, yet population‐based data on survival and risk factors remain limited. This study aimed to describe survival in a large national RB cohort and identify predictors of death and complications.
Samuel Sassine, Ofélie Trudeau‐Ferrin, Caroline Laverdière, Patrick Hamel, Rosanne Superstein, Bénédicte Koukoui, Carole Provost, Paul C. Nathan, Vijay Ramaswamy, Furqan Shaikh, Brenda Gallie, Ashwin Mallipatna, Stephanie Kletke, Helen Dimaras, Hallie Coltin   +14 more
wiley   +1 more source

Kluth type IIIb9variant of esophageal atresia

Journal of Indian Association of Pediatric Surgeons, 2020
We, herein, present an extremely rare case of an esophageal atresia (EA) with distal tracheoesophageal fistula (TEF) with additional perforated membrane at the lower one-third of fistula.
Rahul Gupta, Ankit Singh, Arun Kumar Gupta   +2 more
doaj   +1 more source

A bivalent recombinant vaccine targeting the S1 protein induces neutralizing antibodies against both SARS‐CoV‐2 variants and wild‐type of the virus

MedComm, 2021
The emerging variants of severe acute respiratory syndrome coronavirus‐2 (SARS‐CoV‐2) in pandemic call for the urgent development of universal corona virus disease 2019 (COVID‐19) vaccines which could be effective for both wild‐type SARS‐CoV‐2 and mutant
Cai He, Jingyun Yang, Xuemei He, Weiqi Hong, Hong Lei, Zimin Chen, Guobo Shen, Li Yang, Jiong Li, Zhenling Wang, Xiangrong Song, Wei Wang, Guangwen Lu, Xiawei Wei   +13 more
doaj   +1 more source

Multiparty quantum secret sharing of secure direct communication [PDF]

, 2005
Based on the two-step protocol [Phys. Rev. A68(03)042317], we propose a $(n,n)$-threshold multiparty quantum secret sharing protocol of secure direct communication.
Bagherinezhad, Bandyopadhyay, Beige, Bennett, Boström, Bradler, Chau, Cleve, Deng, Deng, Gottesman, Gruska, Guo, Hillery, Hsu, Inamori, Karimipour, Karlsson, Kim, Lance, Li, Long, Schneier, Tittel, Waks, Xiao, Zhan-Jun Zhang, Zhang, Zhang, Zhao   +29 more
core   +1 more source

Personalized Selumetinib Dosing in Pediatric Neurofibromatosis Type 1: Insights From a Pilot Therapeutic Drug Monitoring Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Objective To evaluate selumetinib exposure using therapeutic drug monitoring (TDM) in pediatric patients with neurofibromatosis type 1 (NF1) and plexiform neurofibromas (PN), assess interpatient pharmacokinetic variability, and explore the relationship between drug exposure, clinical response, and adverse effects.
Janka Kovács, Zoltán Köllő, Balázs Gellért Karvaly, Mahmoud Obeidat, Rita Nagy, Péter Hegyi, Brigitta Teutsch, Eszter Tuboly, Miklós Garami   +8 more
wiley   +1 more source

Phenotypes of GNAO1 Variants in a Chinese Cohort

Frontiers in Neurology, 2021
This study aimed to analyze the genotypes and phenotypes of GNAO1 variants in a Chinese cohort. Seven male and four female patients with GNAO1 variants were enrolled, including siblings of brothers.
Xiaoling Yang, Xueyang Niu, Ying Yang, Miaomiao Cheng, Jing Zhang, Jiaoyang Chen, Zhixian Yang, Yuehua Zhang   +7 more
doaj   +1 more source

Genetic Variants of CLEC4E and BIRC3 in Damage-Associated Molecular Patterns-Related Pathway Genes Predict Non-Small Cell Lung Cancer Survival

Frontiers in Oncology, 2021
Accumulating evidence supports a role of various damage-associated molecular patterns (DAMPs) in progression of lung cancer, but roles of genetic variants of the DAMPs-related pathway genes in lung cancer survival remain unknown.
Lihua Liu, Lihua Liu, Lihua Liu, Hongliang Liu, Hongliang Liu, Sheng Luo, Edward F. Patz, Edward F. Patz, Edward F. Patz, Carolyn Glass, Carolyn Glass, Li Su, Lijuan Lin, David C. Christiani, David C. Christiani, Qingyi Wei, Qingyi Wei, Qingyi Wei   +17 more
doaj   +1 more source

Adherence to Protocol Recommendations for Children With Wilms Tumour in Two Consecutive Studies in the United Kingdom and Ireland—Does Variation Matter?

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background and Aims Wilms tumour (WT) has excellent event‐free and overall survival (OS). However, small differences exist between countries participating in the same international study. This led us to examine variation in adherence to protocol recommendations as a potential contributing factor.
Suzanne Tugnait, R. Al‐Saadi, A. Lopez‐Cortes, K. Dzhuma, M. Oostveen, J. Brok, S. Irtan, M. Weeks, J. Bate, S. Baker, R. Williams, M. Powis, D. Saunders, O. Olsen, T. Watson, S. Shelmerdine, S. Vaidya, L. Howell, C. Duncan, G. M. Vujanic, C. Stiller, G. P. Balchin, T. Chowdhury, K. Pritchard‐Jones   +23 more
wiley   +1 more source

Vitamin D status in Faroese adults and its association with inflammatory bowel diseases - a cross-sectional study from the FarGen 2 project

International Journal of Circumpolar Health
Vitamin D is vital for physiological functions and is obtained primarily through sunlight and a few dietary sources. With limited sunlight exposure, the Faroe Islands face challenges in maintaining sufficient levels of vitamin D, while the Faroese ...
Randi Næss Lisberg, Kári Rubek Nielsen, Leivur Nattestad Lydersen, Katrin Didriksen Apol, Jóngerð Midjord, Olivia Gray, Melissa Hendershott, Marin Strøm, Noomi Oddmarsdóttir Gregersen   +8 more
doaj   +1 more source