Results 31 to 40 of about 1,033,098 (269)

Genomic Diversity and Clinical Variability in Pediatric Primary Cutaneous Anaplastic Large Cell Lymphoma: A Case Series

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Primary cutaneous anaplastic large cell lymphoma (pcALCL) is a rare pediatric CD30‐positive T‐cell lymphoproliferative disorder with an excellent prognosis, but its genomic drivers are poorly defined. We report three children with skin‐limited disease demonstrating striking molecular heterogeneity, including NPM::ALK, NUP214::FRK, and a novel ...
Shoshana Greenberger, Efrat Bar‐Ilan, Victoria Marcu, Evgeny Grishin, Rinat Yacobi, Aviv Barzilai, Hana Golan, Assaf Arie Barg   +7 more
wiley   +1 more source

Effect of vitamin D status on adult COVID-19 pneumonia induced by Delta variant: A longitudinal, real-world cohort study

Frontiers in Medicine, 2023
ObjectiveThe effect of vitamin D status on adult COVID-19 pneumonia induced by Delta variant remains to be further explored.MethodsA longitudinal, real-world cohort study was performed.
Hua Huang, Jiawei Zheng, Yan Liu, Qunhe Zhou, Denggao Peng   +4 more
doaj   +1 more source

The Combined Effect of Obesity and Contraceptive Use on Pulmonary Embolism in Adolescent Females Residing in the United States

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Combined oral contraceptive (COC) use in obese adult women dramatically increases the relative risk of developing a pulmonary embolism (PE). The risk of a PE in obese adolescent females taking contraceptives is currently unknown. The purpose of this investigation was to determine the effect of body mass index (BMI) and contraceptive
John Puetz, Joanne Salas
wiley   +1 more source

The cis-Regulatory Element of SNCA Intron 4 Modulates Susceptibility to Parkinson’s Disease in Han Chinese

Frontiers in Genetics, 2020
Objective: A novel functional cis-regulatory element (CRE) located at SNCA intron 4 has recently been identified in association with Parkinson’s disease (PD) risk in European descendants.
Shi-Guo Zhu, Shi-Guo Zhu, Hui Lu, Miao Mao, Zhao-Feng Li, Lei Cui, Begench Ovlyakulov, Xiong Zhang, Jian-Hong Zhu, Jian-Hong Zhu   +9 more
doaj   +1 more source

Are Fertility Preservation Procedures Before Gonadotoxic Therapy and Hematopoietic Stem Cell Transplantation Feasible and Safe in Very Young Children? A Retrospective Cohort Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Fertility preservation (FP) is increasingly integrated into the care of pediatric patients exposed to gonadotoxic therapy or conditioning for hematopoietic stem cell transplantation (HSCT), yet perioperative data in infants and toddlers remain scarce.
Kerstin Saalabian, Yannick Braun, Till‐Martin Theilen, Anke Barnbrock, Theresa Rohm, Fabienne Hammant, Nicole Sänger, Aynura Abbasova‐Semiz, Jan‐Henning Klusmann, Thomas Klingebiel, Udo Rolle, Peter Bader, Henning C. Fiegel, Andrea Jarisch   +13 more
wiley   +1 more source

Kluth type IIIb9variant of esophageal atresia

Journal of Indian Association of Pediatric Surgeons, 2020
We, herein, present an extremely rare case of an esophageal atresia (EA) with distal tracheoesophageal fistula (TEF) with additional perforated membrane at the lower one-third of fistula.
Rahul Gupta, Ankit Singh, Arun Kumar Gupta   +2 more
doaj   +1 more source

A bivalent recombinant vaccine targeting the S1 protein induces neutralizing antibodies against both SARS‐CoV‐2 variants and wild‐type of the virus

MedComm, 2021
The emerging variants of severe acute respiratory syndrome coronavirus‐2 (SARS‐CoV‐2) in pandemic call for the urgent development of universal corona virus disease 2019 (COVID‐19) vaccines which could be effective for both wild‐type SARS‐CoV‐2 and mutant
Cai He, Jingyun Yang, Xuemei He, Weiqi Hong, Hong Lei, Zimin Chen, Guobo Shen, Li Yang, Jiong Li, Zhenling Wang, Xiangrong Song, Wei Wang, Guangwen Lu, Xiawei Wei   +13 more
doaj   +1 more source

Central Nervous System Neuroblastoma, FOXR2‐Activated: A Pooled Analysis of Published Clinical Outcomes

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Central nervous system (CNS) neuroblastoma, FOXR2‐activated, is a recently recognized entity in the WHO CNS5 classification, defined by activation of the FOXR2 transcription factor and unique histopathological features. This review synthesizes available literature and pooled clinical data, providing insight into demographics ...
Sudarshawn Damodharan, Mohamed S. Abdelbaki   +1 more
wiley   +1 more source

Faroese whole genomes provide insight into ancestry and recent selection

eLife
The Faroe Islands are home to descendants of a North Atlantic founder population with a unique history shaped by both migration and periods of relative isolation.
Iman Hamid, Ólavur Mortensen, Alba Refoyo-Martínez, Leivur N Lydersen, Anne-Katrin Emde, Melissa Hendershott, Katrin D Apol, Guðrið Andorsdóttir, Jonas Meisner, Kaja A Wasik, Fernando Racimo, Stephane E Castel, Noomi O Gregersen   +12 more
doaj   +1 more source

Phenotypes of GNAO1 Variants in a Chinese Cohort

Frontiers in Neurology, 2021
This study aimed to analyze the genotypes and phenotypes of GNAO1 variants in a Chinese cohort. Seven male and four female patients with GNAO1 variants were enrolled, including siblings of brothers.
Xiaoling Yang, Xueyang Niu, Ying Yang, Miaomiao Cheng, Jing Zhang, Jiaoyang Chen, Zhixian Yang, Yuehua Zhang   +7 more
doaj   +1 more source