Results 41 to 50 of about 3,099,093 (291)

The Design and Characterization of Receptor-selective APRIL Variants [PDF]

Journal of Biological Chemistry, 2012
A proliferation-inducing ligand (APRIL), a member of the TNF ligand superfamily with an important role in humoral immunity, is also implicated in several cancers as a prosurvival factor. APRIL binds two different TNF receptors, B cell maturation antigen (BCMA) and transmembrane activator and cylclophilin ligand interactor (TACI), and also interacts ...
Kimberley Fiona C, van der Sloot Almer M, Guadagnoli Marco, Cameron Katherine, Schneider Pascal, Marquart J Arnoud, Versloot Miranda, Serrano Luis, Medema Jan Paul   +8 more
openaire   +3 more sources

Ovarian Sex Cord Stromal Tumors in Children and Adolescents—The European Standard Clinical Practice Recommendations

Pediatric Blood &Cancer, EarlyView.
ABSTRACT As part of the European Cooperative Study Group for Paediatric Rare Tumours initiative, we developed standard clinical practice guidelines for ovarian sex cord stromal tumors, based on comprehensive national and international cohort analyses, literature review, and a final expert consensus conference.
Dominik T. Schneider, Kris‐Ann Schultz, Nora Schnitzler, Michael Abele, Tal Ben‐Ami, Ewa Bien, Gianni Bisogno, Ines B. Brecht, Maja Cesen, Andrea Ferrari, Michaela Kuhlen, Malgorzata A. Krawczyk, Ricardo Lopez‐Almaraz, Yves Reguerre, Calogero Virgone, Daniel Orbach   +15 more
wiley   +1 more source

Evidence‐Informed Multidisciplinary Consensus Guidance for the Psychosocial Care of Adolescents With High‐Risk Cancer: Recommendations From the Italian Association of Pediatric Hematology and Oncology

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Adolescents with high‐risk cancer face complex developmental, psychosocial, and ethical challenges that extend beyond disease‐directed treatment. Although international recommendations exist for communication, psychosocial care, pediatric palliative care, survivorship, and shared decision‐making, these have largely evolved within ...
Johanna M. C. Blom, Dorella Scarponi, Giulia Zucchetti, Teresa Perillo, Maria Montanaro, Elisa Marconi, Chiara Rutigliano, Paolo Colavero, Paola Quarello, Marina Bertolotti, Monica Cellini, Carlo Clerici, Maurizio Mascarin, Francesca Bomben, Andrea Ferrari, the expert workgroup   +15 more
wiley   +1 more source

Effect of tensile deformation on variant selection in {225}γ plate martensite and {557}γ lath martensite

Results in Materials, 2019
The effect of tensile deformation on variant selection has been studied in {225}γ plate martensite and {557}γ lath martensite formed in high- and low-carbon steels, respectively.
Annick P. Baur, Cyril Cayron, Roland E. Logé   +2 more
doaj   +1 more source

The population frequency of human mitochondrial DNA variants is highly dependent upon mutational bias

Biology Open, 2021
Next-generation sequencing can quickly reveal genetic variation potentially linked to heritable disease. As databases encompassing human variation continue to expand, rare variants have been of high interest, since the frequency of a variant is expected ...
Cory D. Dunn
doaj   +1 more source

Bridging the Loneliness Gap: Depression, Connectivity, and Isolation in Pediatric Oncology Patients and Their Peers

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Loneliness is associated with adverse physical and mental health outcomes and remains understudied in children and adolescents undergoing cancer therapy. Pediatric oncology patients may be at increased risk due to medical isolation and disruption of social networks.
Charlotte N. Stahlfeld, Scott H. Maurer, Michelle D. Watkinson, John Nury, Elise Barberis, Molly C. Mack   +5 more
wiley   +1 more source

Heat treatment effects and variant selection in multi-material laser powder bed fusion of FeNi- and CoCr-based alloys

Virtual and Physical Prototyping
This study demonstrates the successful fabrication of a multi-material 18Ni(300) maraging steel – CoCrMo alloy using laser powder bed fusion (L-PBF), which in its as-built state, displays suboptimal mechanical performance.
Jubert Pasco, Ali Keshavarzkermani, Kudakwashe Nyamuchiwa, Lu Jiang, Thomas Dorin, Clodualdo Aranas Jr   +5 more
doaj   +1 more source

APEKS — a method of decision making

Science, Technology and Innovation, 2021
The APEKS method was developed in the 1970s. It has a wide range of applications for making a decision. The article describes the APEKS method, which is a multi-criteria method and consists of 10 steps. The application of this method was presented in the
Jan Szybka, Sylwester Pabian
doaj   +1 more source

Fecal Influenza in Mammals: Selection of Novel Variants [PDF]

Journal of Virology, 2013
ABSTRACT In aquatic birds, influenza A viruses mainly replicate in the intestinal tract without significantly affecting the health of the host, but in mammals, they replicate in the respiratory tract and often cause disease. Occasionally, influenza viruses have been detected in stool samples of hospitalized patients and in rectal
Russell, Charles J., Zhang, Jinghui, Zaraket, Hassan, Obenauer, John, KOÇER, ZEYNEP AHSEN, Webstera, Robert G., Rehg, Jerold E.   +6 more
openaire   +3 more sources

Source of variant Creutzfeldt-Jakob disease outside United Kingdom. [PDF]

, 2007
We studied the occurrence of variant Creutzfeldt-Jakob disease (vCJD) outside the United Kingdom in relation to the incidence of indigenous bovine spongiform encephalopathy (BSE) and to the level of live bovines and bovine products imported from the UK ...
Cousens, Simon N, Cornelia M. van Duijn, Sanchez-Juan, Pascual, Pascual Sanchez-Juan, Will, Robert G, van Duijn, Cornelia M, Robert G. Will, Pascual Sanchez-Juan, Simon N. Cousens   +8 more
core   +1 more source