Results 21 to 30 of about 3,445,859 (230)
Variation diminishing property with b = 1 p = 3 k = 1.
Variation diminishing property with b = 1 p = 3 k = 1.
Abdul Majeed (725054) +2 more
core +1 more source
Reflexivity in Meadow Mari: Binding and Agree [PDF]
According to the Canonical Binding Theory (Chomsky 1981), anaphors must be bound in their local domain and pronominals must be free. The discovery of “long-distance anaphors” (e.g.
Volkova, Anna, ILS Variation
core +2 more sources
Intellectual Property Ordering beyond Borders
This volume offers a broad range of perspectives on how intellectual property rights are protected beyond borders and highlights how public international law is an under-researched common denominator in the global protection of IP rights.
core +1 more source
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
wiley +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
Variation diminishing properties of Bernstein polynomials on triangles
Let T be a triangle, \(f: T\to R\), \(B_ n(f,T)=Bn(f)\) the Bernstein polynomial of degree n and \(\{\hat f{}_ n\}\) the net of Bézier of order n for f on T. Let \(V(f,T)=\int_{T}(f^ 2_ x+f^ 2_ y)^{1/2} dT\) and \(V_ 1(f,T)=\int_{T}(f^ 2_{xx}+2f^ 2_{xy}+f^ 2_{yy})^{1/2} dT.\) Then the following results hold: 1) For any \(n\geq 1\) we have \(V_ 1(B_ n(f)
openaire +2 more sources
Design and analysis strategies for robust microbiome ageing research
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
An Advection Scheme using Paired Explicit Runge-Kutta Time Integration for Atmospheric Modeling
In this paper, a new numerical scheme was proposed to solve the advection equation in a multi-moment nonhydrostatic dynamical core.To guarantee the shape-preserving property, the limiting operations are devised for a hybrid discretization framework ...
Zhaoyang SUN +3 more
doaj +1 more source

