Results 111 to 120 of about 9,552,128 (326)

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

FEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

Assessing the accuracy of the program Stature for stature estimation in White South Africans

Forensic Science International: Reports
In 2016, Polcerová and Králik created an open-access software program, Stature, designed to automate the estimation of living stature in forensic and archaeological cases.
Natasha R. Loubser, Amy J. Spies, Desiré Brits   +2 more
doaj   +1 more source

Spatiotemporal variations of “triple-demic” outbreaks of respiratory infections in the United States in the post-COVID-19 era [PDF]

, 2023
Wei Luo, Qianhuang Liu, Yuxuan Zhou, Yiding Ran, Zhaoyin Liu, Weitao Hou, Sen Pei, Shengjie Lai   +7 more
openalex   +1 more source

The role of histone modifications in transcription regulation upon DNA damage

FEBS Letters, EarlyView.
This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley   +1 more source

Spatio-temporal Variation of Meteorological Influence on PM2.5 and PM10 over Major Urban Cities of Bangladesh [PDF]

, 2022
Nafisa Islam, Tarik Reza Toha, Mohammad Maksimul Islam, Tanvir Ahmed   +3 more
openalex   +1 more source

Nicotinamide N‐methyltransferase promotes drug resistance in lung cancer, as revealed by nascent proteomic profiling

Molecular Oncology, EarlyView.
AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou, Zhen Wang, Fei Yang, Xiao Han, Lei Li, Huadong Liu   +5 more
wiley   +1 more source

Variation among wheat (Triticum easativumL.) genotypes in response to the drought stress: I – selection approaches [PDF]

, 2018
Stanisław Grzesiak, Natalia Hordyńska, P. Szczyrek, Maciej T. Grzesiak, Angelika Noga, Magdalena Szechyńska‐Hebda   +5 more
openalex   +1 more source

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham, Jasibel Vasquez‐Gonzalez, Samantha M. Barnada, Salome Tchotorlishvili, Latese Jones, Ryan Maguire, Genevieve Lewis, Kinza Rizwan, Jenny Deng, Salma Koachar, Drithi Patel, Hailey Shankle, Tessa Mulders, Namra Ajmal, Charalambos Solomides, Emad S. Alnemri, Teresa F. Alnemri, Ayesha A. Shafi, Leonard G. Gomella, Wm Kevin Kelly, Steven B. McMahon, Matthew J. Schiewer   +21 more
wiley   +1 more source

Nutritional anthropology in the world

Journal of Physiological Anthropology
Nutritional anthropology is the study of human subsistence, diet and nutrition in comparative social and evolutionary perspective. Many factors influence the nutritional health and well-being of populations, including evolutionary, ecological, social ...
Stanley Ulijaszek
doaj   +1 more source

Grand Unification and Time Variation of the Gauge Couplings

, 2002
Astrophysical indications that the fine structure constant is time dependent are discussed in the framework of grand unification models. A variation of the electromagnetic coupling constant could either be generated by a corresponding time variation of ...
Calmet, X., Fritzsch, H.
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