Results 91 to 100 of about 7,284,216 (310)

Integration of short non coding RNA and genetic factors for coronary artery disease risk prediction in a prospective study

Scientific Reports
Coronary artery diseases (CADs) continue to be the leading global contributors to multi-morbidity and mortality. Given the significant burden of CADs, there is a critical need to identify novel and effective biomarkers for risk assessment.
Elisabetta Casalone, Miriam Rosselli, Giovanni Birolo, Carla Debernardi, Chiara Catalano, Serena Aneli, Alessandra Allione, Cecilia Di Primio, Annette Peters, Christian Gieger, Gabrielle Anton, Paolo Vineis, Carlotta Sacerdote, Giuseppe Matullo   +13 more
doaj   +1 more source

Using eQTL weights to improve power for genome-wide association studies: a genetic study of childhood asthma

Frontiers in Genetics, 2013
Increasing evidence suggests that single nucleotide polymorphisms (SNPs) associated with complex traits are more likely to be expression quantitative trait loci (eQTLs).
Lin eLi, Michael eKabesch, Emmanuelle eBouzigon, Emmanuelle eBouzigon, Florence eDemenais, Florence eDemenais, Martin eFarrall, Miriam F. Moffatt, Xihong eLin, Liming eLiang, Liming eLiang   +10 more
doaj   +1 more source

Re‐Irradiation in Pediatric Diffuse Midline Glioma: A Multi‐Institutional Retrospective Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Children with recurrent diffuse midline gliomas (DMGs) have limited therapeutic options at recurrence. Re‐irradiation (RT2) may be used at progression, but with uncertainty about the benefit. Methods We conducted a multi‐institutional retrospective study of children aged < 18 with DMG treated at three centers (Toronto, Canada ...
Ajay Thomas Alex, Sean P. Hassan, Helen Benghiat, Liam Herbert, Jennifer Adamski, Shivani Bailey, Claire Esler, Louise Brookes, Molly Bamber, Grace Koudou, Karen Waite, Julie Bennett, Anirban Das, Derek S. Tsang   +13 more
wiley   +1 more source

An integrated map of structural variation in 2,504 human genomes

Nature, 2015
Structural variants are implicated in numerous diseases and make up the majority of varying nucleotides among human genomes. Here we describe an integrated set of eight structural variant classes comprising both balanced and unbalanced variants, which we
Peter Sudmant, T. Rausch, E. Gardner, R. Handsaker, A. Abyzov, J. Huddleston, Yan Zhang, Kai Ye, Goo Jun, M. H. Fritz, Miriam K. Konkel, A. Malhotra, A. Stütz, Xinghua Shi, F. P. Casale, Jieming Chen, F. Hormozdiari, Gargi Dayama, Ken Chen, Maika Malig, Mark J. P. Chaisson, Klaudia Walter, Sascha Meiers, Seva Kashin, Erik P. Garrison, A. Auton, Hugo Y. K. Lam, X. Mu, Can Alkan, D. Antaki, Taejeong Bae, Eliza Cerveira, P. Chines, Zechen Chong, Laura Clarke, E. Dal, L. Ding, Sarah B. Emery, Xian Fan, Madhusudan Gujral, Fatma Kahveci, J. Kidd, Yu Kong, Eric-Wubbo Lameijer, Shane A. McCarthy, Paul Flicek, R. Gibbs, Gabor T. Marth, C. Mason, A. Menelaou, D. Muzny, Bradley J. Nelson, Amina Noor, N. Parrish, Matthew Pendleton, Andrew Quitadamo, B. Raeder, E. Schadt, Mallory Romanovitch, A. Schlattl, R. Sebra, A. Shabalin, A. Untergasser, Jerilyn A. Walker, Min Wang, F. Yu, Chengsheng Zhang, Jing Zhang, Xiangqun Zheng-Bradley, Wanding Zhou, T. Zichner, J. Sebat, M. Batzer, S. Mccarroll, Ryan E. Mills, M. Gerstein, A. Bashir, O. Stegle, S. Devine, Charles Lee, E. Eichler, J. Korbel   +81 more
semanticscholar   +1 more source

Association Between Dinutuximab Beta Exposure and Post‐End‐of‐Treatment Survival in Neuroblastoma: A Weighted Patient‐Level Analysis of Three Clinical Studies

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Objectives The association between exposure to dinutuximab beta (DB) and event‐free survival (EFS) or overall survival (OS) of neuroblastoma patients was assessed using data collected during three clinical trials (five cohorts). Methods A systematic review (March 2026) was conducted to identify relevant studies (prospective; registered DB ...
Przemysław Holko, Holger N. Lode, Alberto Garaventa, Carla Manzitti, Roberto Luksch, Dominique Valteau‐Couanet, Marion Gambart, John Anderson, Juliet Gray, Adela Canete, Lucas Moreno, Aleksandra Wieczorek, Cormac Owens, Shifra Ash, Isaac Yaniv, Genevieve Laureys, Hans Loibner, Katarzyna Śladowska, Ruth Ladenstein, Paweł Kawalec   +19 more
wiley   +1 more source

Long‐Term Outcomes of Patients With Relapsed/Refractory Neuroblastoma Treated on ANBL1221: A Report From the Children's Oncology Group

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Results of COG ANBL1221 changed treatment paradigms for patients with relapsed/refractory neuroblastoma. Chemoimmunotherapy with irinotecan/temozolomide/dinutuximab is now used as both bridge therapy following suboptimal response to induction and as treatment in first relapse.
Elizabeth Sokol, Arlene Naranjo, Lulu Chen, Rajen Mody, Steven G. DuBois, Rochelle Bagatell, Navin Pinto   +6 more
wiley   +1 more source

Analysis of the Future Distribution and Trend of Arctic Sea Ice Using CMIP6 Data

Haiyang Kaifa yu guanli
This study examines the future spatial distributions and long-term trends of the sea ice concentration (SIC) and the sea ice thickness (SIT) in the Arctic, along with the potential impacts of the Temperature at Surface (TAS), using the outputs of six ...
SHI Xudong, HE Tao, LI Min, LI Bingrui, LIU Simeng, XIE Lingling   +5 more
doaj  

Decadal Regime Shifts in Sea Fog Frequency over the Northwestern Pacific: The Influence of the Pacific Decadal Oscillation and Sea Surface Temperature Warming

Atmosphere
Sea fog significantly impacts marine activities, ecosystems, and radiation balance. We analyzed the decadal variation characteristics of sea fog frequency (SFF) over the northwestern Pacific and investigated the roles of the Pacific decadal oscillation ...
Shihan Zhang, Liguo Han, Jingchao Long, Lingyu Dong, Pengzhi Hong, Feng Xu   +5 more
doaj   +1 more source

BMT4me En Español: Multisite Feasibility and Usability Testing of a Spanish‐Language mHealth Adherence Support App for Spanish‐Speaking Caregivers of Children After Hematopoietic Stem Cell Transplantation and Cancer Treatment

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Medication nonadherence during the first 100 days after pediatric hematopoietic stem cell transplantation (HSCT) and during oncology treatment increases risk for complications. BMT4me is a caregiver‐facing mobile health (mHealth) application providing medication reminders, symptom tracking, and note‐taking features to support ...
Micah A. Skeens, Madeline R. Peek, Bianca Franklin, Emre Sezgin, Melissa Beauchemin   +4 more
wiley   +1 more source

Efficient sentence processing significantly affects the position of objects in Russian

Linguistics
In this article we explore various properties of direct objects in Russian that may condition the preference for a preverbal versus postverbal position of the object, against the general trend towards VO constituent order in Russian.
Seržant Ilja A., Alfimova Daria, Biskup Petr, Seržants Ivan   +3 more
doaj   +1 more source