Results 71 to 80 of about 7,284,216 (310)
ABSTRACT Background Acute lymphoblastic leukemia (ALL) is the most common pediatric cancer, with an overall survival now surpassing 90% in developed countries. However, treatments are not without adverse effects. In this study, we apply the severe toxicity‐free survival (STFS) framework to determine the prevalence of 21 physician‐defined severe ...
Lane Collier +10 more
wiley +1 more source
Applicability Evaluation of Antarctic Ozone Reanalysis and Merged Satellite Datasets
In this study, based on total column ozone observations from eight Antarctic stations, we evaluate the applicability of ERA5, C3S-MSR, MERRA-2, and JRA-55 reanalysis datasets and the NIWA-BS merged satellite dataset, in terms of interannual variation and
Junzhe Chen +4 more
doaj +1 more source
ABSTRACT Background Type 1 plasminogen deficiency (PLGD‐1) is an ultra‐rare autosomal recessive disorder caused by variants in the PLG gene and affects approximately 1.6 individuals per million. The condition is characterized by decreased plasminogen levels and impaired function, resulting in fibrin‐rich lesions on mucous membranes throughout the body.
Charles Nakar +7 more
wiley +1 more source
Systematic Localization of Common Disease-Associated Variation in Regulatory DNA
Predictions of Genetic Disease Many genome-wide association studies (GWAS) have identified loci and variants associated with disease, but the ability to predict disease on the basis of these genetic variants remains small. Maurano et al. (p.
Matthew T. Maurano +31 more
semanticscholar +1 more source
This paper presents similarities in data by expressing them as a new type. Instead of copy-pasting a group of similar data elements, it is packed up in a class or structure and then many instances of it is created.
openaire +2 more sources
ABSTRACT Introduction The use of herbal medical preparation (HMP) is rising among pediatric oncology patients, often to manage treatment‐related symptoms. Their effectiveness remains uncertain, and the risk of herb–drug interactions is underestimated.
Orianne Mahot +6 more
wiley +1 more source
Schizophrenia risk from complex variation of complement component 4
Schizophrenia is a heritable brain illness with unknown pathogenic mechanisms. Schizophrenia’s strongest genetic association at a population level involves variation in the major histocompatibility complex (MHC) locus, but the genes and molecular ...
Aswin Sekar +16 more
semanticscholar +1 more source
On husserlian eidetic variation and its duplicity: “contingency-variation” or “similarity-variation”? [PDF]
Whoever deals with the issue of eidos in Husserl’s phenomenology cannot repress an uncomfortable sensation due to the fact that, if on the one hand the Husserlian Denkweg unfolds itself unitarily, at least at the level of a certain number of basic methodological acquisitions (and eidetic analysis is to number among these), on the other hand the ...
openaire +2 more sources
ABSTRACT Pediatric radiation therapy presents unique challenges compared to adult treatments, including those of immobilization, potential need for sedation, and the critical importance of accurate, reproducible positioning. Additionally, heightened attention to imaging doses is necessary to minimize long‐term toxicity in survivors.
Parham Alaei +17 more
wiley +1 more source
Personalized Zebrafish Models for Fusion‐Positive Pediatric Sarcomas
ABSTRACT Clinical sequencing efforts have revolutionized our approaches to categorizing pediatric cancers in real time. This has dramatically improved our ability to profile pediatric tumors, identify actionable vulnerabilities, and influence clinical care.
Lisa H. Hall +2 more
wiley +1 more source

