Results 191 to 200 of about 7,252,224 (344)

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

open access: yesMolecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici   +8 more
wiley   +1 more source

Implications for conifer glacial refugia and postglacial climatic variation in western Beringia from lake sediments of the Upper Indigirka basin

open access: green, 2018
Anatoly Lozhkin   +8 more
openalex   +2 more sources

Measuring spatial variation in secondary production and food quality using a common consumer approach in Lake Erie [PDF]

open access: bronze, 2016
James H. Larson   +8 more
openalex   +1 more source

PYCR1 inhibition in bone marrow stromal cells enhances bortezomib sensitivity in multiple myeloma cells by altering their metabolism

open access: yesMolecular Oncology, EarlyView.
This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert   +13 more
wiley   +1 more source

Inequitable Variation

open access: yesJournal of the Royal College of Physicians of London, 1996
openaire   +2 more sources

Home - About - Disclaimer - Privacy