Results 61 to 70 of about 558,212 (268)

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

Semen quality analysis of military personnel from six geographical areas of the People’s Republic of China [PDF]

open access: yes, 2011
Objective: To examine the determinants of semen quality in a large sample of military personnel from different geographical areas of the People's Republic of China. Design: Cross-sectional study.
Haixiang Hu   +15 more
core   +1 more source

Dental morphology and variation across holocene Khoesan people of Southern Africa [PDF]

open access: yes, 2014
Includes bibliographical references.Dental analyses of the Holocene Khoesan populations of southern Africa can provide insight into the biological evolution of an anthropologically important people.
Black, Wendy
core   +1 more source

The microbiome in human skin aging

open access: yesFEBS Letters, EarlyView.
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana   +3 more
wiley   +1 more source

Infection and co-infection with helminths and Plasmodium among school children in Côte d'Ivoire : results from a National Cross-Sectional Survey [PDF]

open access: yes, 2014
Helminth infection and malaria remain major causes of ill-health in the tropics and subtropics. There are several shared risk factors (e.g., poverty), and hence, helminth infection and malaria overlap geographically and temporally.
Silué, Kigbafori D.   +35 more
core   +2 more sources

Individual variation in migration patterns of Iberian little bustards

open access: yesMovement Ecology
Background Migration is a critical behavioural strategy across many taxa, allowing individuals to respond to seasonal shifts in environmental conditions and resource availability.
Filipa Coutinho Soares   +11 more
doaj   +1 more source

Functional comparison of EncB and EncC cargo proteins in iron storage within the Myxococcus xanthus encapsulin

open access: yesFEBS Letters, EarlyView.
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell   +2 more
wiley   +1 more source

The etiology of esophageal cancer in high- and low- risk areas of Jiangsu province, China [PDF]

open access: yes, 2011
[Background]Esophageal cancer (EC) remains one of the most common and fatal malignancies worldwide. The geographic variation in EC occurrence is striking, and China is an area with one of the highest incidences of EC.
Wu, M.
core  

Spatial and temporal patterns of locally-acquired dengue transmission in northern Queensland, Australia, 1993-2012.

open access: yesPLoS ONE, 2014
BackgroundDengue has been a major public health concern in Australia since it re-emerged in Queensland in 1992-1993. We explored spatio-temporal characteristics of locally-acquired dengue cases in northern tropical Queensland, Australia during the period
Suchithra Naish   +5 more
doaj   +1 more source

Chiral separation of chloroalkanes with the chromatographic column onboard Martian rovers

open access: yesFEBS Letters, EarlyView.
Computer image of the Rosalind Franklin Rover of ESA's ExoMars mission. ExoMars is scheduled to land on planet Mars in Oxia Planum in 2029. This area represents an interesting spot to look for biosignatures. Investigations of ExoMars include measurement on molecular chirality. We show that chiral chloroalkanes, that have been identified on Mars, can be
Asma Merzougui   +4 more
wiley   +1 more source

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