Results 71 to 80 of about 558,212 (268)

Geographical variation in rates of surgical treatment for female stress urinary incontinence in England: a national cohort study

BMJ Open, 2019
Objective To examine geographic variation in use of surgery for female stress urinary incontinence (SUI), mainly midurethral mesh tape insertions, in the English National Health Service (NHS).Design National cohort study.Setting NHS hospitals ...
Jan H van der Meulen, David A Cromwell, Andrew Wilson, Tahir Mahmood, Ash Monga, Jil B Mamza, Rebecca S Geary, Dina El-Hamamsy, Jonathan Duckett, Philip Toozs-Hobson, Douglas G Tincello, Ipek Gurol Urganci   +11 more
doaj   +1 more source

Membrane composition and thermodynamic identity as boundaries of life for synthetic cell research

FEBS Letters, EarlyView.
What makes a cell a cell? The boundary of a living cell is not just a wall. Read as a Markov blanket, the membrane separates internal from external states, generating identity and non‐equilibrium order. Can this identity be rebuilt from scratch in a synthetic cell?
Caterina Presutti, Bert Poolman
wiley   +1 more source

Asthma hospitalisation trends from 2010 to 2015: variation among rural and metropolitan Australians [PDF]

, 2017
Background Asthma remains a leading cause of illness, where primary care can assist to reduce hospitalisations through prevention, controlling acute episodes, and overall management of asthma.
Islam, MR, Robins, Shalley, Islam, Md Rafiqul, Ruby Wyett, Md Rafiqul Islam, Wyett, R, Samantha Gardiner, Terry, D, Robins, S, Gardiner, S, Gardiner, Samantha, Ruby, Wyett, Wyett, Ruby, Terry, Daniel, Daniel Terry, Shalley Robins   +15 more
core   +1 more source

Multilevel geographic determinants of smoking and smokeless tobacco use among young men in India: evidence for targeted addiction prevention policies

Addictive Behaviors Reports
Background: Tobacco use among youth in low- and middle-income countries (LMICs), particularly India, remains a critical public health challenge. However, limited research has examined how different geographic determinants distinctly contribute to smoked ...
Lucky Singh, Harsh Kumar Singh, Prashant Kumar Singh, Shashi Kala Saroj, Amit Yadav, Ankur Singh, Shalini Singh   +6 more
doaj   +1 more source

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

Molecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera, Laura Vela‐Martín, Pablo Fernández‐Navarro, José Luis López‐Lorenzo, Javier Cornago, Pilar Llamas, Eduardo Pérez‐Gómez, José Luis Marín‐Rubio, Manuel Fresno, Javier Santos, José Fernández‐Piqueras, María Villa‐Morales   +11 more
wiley   +1 more source

Factors contributing to COPD hospitalisations from 2010 to 2015: variation among rural and metropolitan Australians [PDF]

, 2019
Introduction: Rural and remote populations experience the greatest burden of chronic obstructive pulmonary disease (COPD), the fifth leading cause of death in Australia.
Islam, MR (15538565), Hoang Nguyen (14745367), Terry, DR (15604439), Kim, J-A (15685697)   +3 more
core   +2 more sources

Socioeconomic disparities in diabetes prevalence among the population in Ireland

BMC Public Health
Introduction A large variation in diabetes prevalence by socioeconomic status (SES) persists internationally. This study aimed to quantify the prevalence of diabetes by age and SES and explore the current levels of inequality in the prevalence of ...
Gintare Valentelyte, Naomi Holman, Steven James, Nicholas Clarke, Dominika Bhatia, Kathleen Bennett, Jan Sorensen, Edward W. Gregg   +7 more
doaj   +1 more source

Predicted Excess Cardiovascular Age and a Reverse Socioeconomic Gradient in a Middle-Income Latin American Country: A Population-Based Analysis of 163,889 Peruvians

Journal of Cardiovascular Development and Disease
Predicted cardiovascular age (heart age) translates the risk-factor profile into an equivalent age, which may facilitate interpretation of estimated cardiovascular risk.
Víctor Juan Vera-Ponce, Jhosmer Ballena-Caicedo, Jhofree Einstein Briceño-Chavez, Kevin Cusma-Regalado, Fiorella E. Zuzunaga-Montoya, Julio César Bautista Zuta, Rossmery Leonor Poemape Mestanza   +6 more
doaj   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

Molecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura, Tadahiro Kuribayashi, Johannes Brägelmann, Sachi Okawa, Masataka Taoka, Shunta Mori, Tomoka Nishimura, Takaaki Tanaka, Go Makimoto, Kiichiro Ninomiya, Kammei Rai, Eiki Ichihara, Ryohei Katayama, Katsuyuki Hotta, Masahiro Tabata, Yosuke Togashi, Yoshinobu Maeda, Martin L. Sos, Katsuyuki Kiura, Kadoaki Ohashi   +19 more
wiley   +1 more source

The causes of regional variation in U.S. poverty: A cross-county analysis [PDF]

The persistence of poverty in the modern American economy, with rates of poverty is some areas approaching those of less industrialized nations, remains a central concern among policy makers. Therefore, this study uses U.S.
Dan Rickman
core