Results 111 to 120 of about 188,725,496 (291)
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Molecular Variation and Genomic Function of Citrus Vein Enation Virus. [PDF]
Int J Mol Sci, 2022 Dou R +7 more
europepmc +1 more source
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Eliciting Big Data From Small, Young, or Non-standard Languages: 10 Experimental Challenges [PDF]
, 2019 The aim of this work is to identify and analyze a set of challenges that are likely to be encountered when one embarks on fieldwork in linguistic communities that feature small, young, and/or non-standard languages with a goal to elicit big sets of rich ...
Leivada, Evelina +9 more
core +2 more sources
Горные науки и технологииThe expansion of mining in potash mines has faced the problem of fresh air shortage, which cannot be solved within the current paradigm of self-contained ventilation.
Konstantin A. Chernyi +1 more
doaj +1 more source
Variation in executive function relates to BMI increases in youth who were initially of a healthy weight in the ABCD Study. [PDF]
Obesity (Silver Spring), 2023 Adise S +7 more
europepmc +1 more source
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
A stochastic-geometric model of soil variation
, 2009 P>Stochastic models of soil variation are used in geostatistical analysis, but in general they bear no relation to our mechanistic understanding of the processes in soil that cause its properties to vary spatially.
R. M. Lark, Lark, R. M.
core +1 more source
SLC12A3 Variation and Renal Function in Chinese Patients With Hypertension. [PDF]
Front Med (Lausanne), 2022 Huang CC +9 more
europepmc +1 more source
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
FEBS Letters, EarlyView.Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source