Results 71 to 80 of about 1,347,601 (289)

A posteriori error covariances in variational data assimilation [PDF]

, 2009
The problem of variational data assimilation for a nonlinear evolution model is formulated as an optimal control problem to find some unknown parameters of the model.
Le Dimet, F.X., Scottish Funding Council via GRPE (Funder), Russian Foundation for Basic Research (Funder), Shutyaev, V.P., Gejadze, I.Yu., MOISE Project (Funder)   +5 more
core   +2 more sources

Metric-affine cosmological models and the inverse problem of the calculus of variations. Part II: Variational bootstrapping of the $$\Lambda $$ Λ CDM model

European Physical Journal C: Particles and Fields
The method of variational bootstrapping, based on canonical variational completion, allows one to construct a Lagrangian for a physical theory depending on two sets of field variables, starting from a guess of the field equations for only one such set ...
Ludovic Ducobu, Nicoleta Voicu
doaj   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

A Kind of New Coupled Model for Rossby Waves in Two Layers Fluid

IEEE Access, 2020
In this article, a new model for Rossby waves in two layers fluid is studied. Form the dimensionless baroclinic quasi-geostrophic vortex equations include exogenous and dissipative, the new (2 + 1)-dimensional coupled ZK-mZK equations are established by ...
Runhua Tian, Zongguo Zhang, Baojun Zhao, Hongwei Yang   +3 more
doaj   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

Molecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura, Tadahiro Kuribayashi, Johannes Brägelmann, Sachi Okawa, Masataka Taoka, Shunta Mori, Tomoka Nishimura, Takaaki Tanaka, Go Makimoto, Kiichiro Ninomiya, Kammei Rai, Eiki Ichihara, Ryohei Katayama, Katsuyuki Hotta, Masahiro Tabata, Yosuke Togashi, Yoshinobu Maeda, Martin L. Sos, Katsuyuki Kiura, Kadoaki Ohashi   +19 more
wiley   +1 more source

Equations of motion for variational electrodynamics

Journal of Differential Equations, 2016
We extend the variational problem of Wheeler-Feynman electrodynamics by putting the electromagnetic functional in a local space of absolutely continuous trajectories possessing a derivative (velocities) of bounded variation. Generalizing the calculus of variations for extrema with a finite number of velocity discontinuities (breaking points), we prove ...
openaire   +3 more sources

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

Molecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur, Joel Rodrigues Vitória, Manuel Saiselet, Ligia Craciun, Denis Larsimont, Anne Lefort, Frédérick Libert, Carine Maenhaut, Sabine Costagliola, Maxime Tarabichi, Mirian Romitti, Vincent Detours   +11 more
wiley   +1 more source

Local Fractional Laplace Variational Iteration Method for Solving Linear Partial Differential Equations with Local Fractional Derivative

Discrete Dynamics in Nature and Society, 2014
The local fractional Laplace variational iteration method was applied to solve the linear local fractional partial differential equations. The local fractional Laplace variational iteration method is coupled by the local fractional variational iteration ...
Ai-Min Yang, Jie Li, H. M. Srivastava, Gong-Nan Xie, Xiao-Jun Yang   +4 more
doaj   +1 more source

Model of biodiversity and plant sustainability based on quantum variational optimization [PDF]

E3S Web of Conferences
Plant biodiversity plays an important role in the sustainability of ecosystems and human societies. The resilience of plants in the context of biodiversity relates to their ability to adapt to changing environmental conditions, provide ecosystem services
Mukhamedieva D.T., Raupova M.H.
doaj   +1 more source

Derivation of the Variational Bayes Equations

CoRR, 2019
The derivation of key equations for the variational Bayes approach is well-known in certain circles. However, translating the fundamental derivations (e.g., as found in Beal's work) to Friston's notation is somewhat delicate. Further, the notion of using variational Bayes in the context of a system with a Markov blanket requires special attention. This
openaire   +3 more sources