Results 91 to 100 of about 13,906,445 (282)

Structural Similarity-Based Nonlocal Variational Models for Image Restoration

open access: yes, 2019
© 1992-2012 IEEE. In this paper, we propose and develop a novel nonlocal variational technique based on structural similarity (SS) information for image restoration problems.
Wang, Wei, Li, Fang, Ng, Michael K.
core   +1 more source

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

open access: yesMolecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq   +8 more
wiley   +1 more source

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

open access: yesMolecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park   +6 more
wiley   +1 more source

BRAIN MR IMAGE SEGMENTATION BY MODIFIED ACTIVE CONTOURS AND CONTOURLET TRANSFORM

open access: yesICTACT Journal on Image and Video Processing, 2017
Multiresolution analysis is often used for image representation and processing because it can represent image at the split resolution and scale space.
P Nageswara Reddy   +2 more
doaj   +1 more source

Translating whole‐genome doubling into precision medicine in cancer

open access: yesMolecular Oncology, EarlyView.
Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley   +1 more source

Refined Iterative Method for a Common Variational Inclusion and Common Fixed-Point Problem with Practical Applications

open access: yesAxioms
This paper introduces a novel parallel method for solving common variational inclusion and common fixed-point (CVI-CFP) problems. The proposed algorithm provides a strong convergence theorem established under specific conditions associated with the CVI ...
Chaiporn Thangthong   +3 more
doaj   +1 more source

Automatic Construction of Accurate Image Processing using AdaBoost [PDF]

open access: yes, 2009
Image processing and recognition technologies are required to solve various problems. We have already proposed the system which automatically constructs image processing with Genetic Programming (GP), Automatic Construction of Tree-structural Image ...
Ando, Jun, Nagao, Tomoharu
core  

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

open access: yesMolecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

CEACAM1 participation in breast cancer progression

open access: yesMolecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin   +3 more
wiley   +1 more source

Nonlinear optimisation method for image segmentation and noise reduction using geometrical intrinsic properties

open access: yes, 2006
This paper considers the optimisation of a nonlinear functional for image segmentation and noise reduction. Equations optimising this functional are derived and employed to detect edges using geometrical intrinsic properties such as metric and Riemann ...
Sharif, Bayan, Mahmoodi, Sasan
core   +1 more source

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