Results 121 to 130 of about 31,536,622 (369)

BMP antagonist CHRDL2 enhances the cancer stem‐cell phenotype and increases chemotherapy resistance in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Overexpression of CHRDL2 in colon cancer cells makes them more stem‐like and resistant to chemo‐ and radiotherapy. CHRDL2‐high cells have upregulation of the WNT pathway, genes involved in the DNA damage response (DDR) pathway and epithelial‐to‐mesenchymal transition (EMT). This leads to quicker repair of damaged DNA and more cell migration.
Eloise Clarkson, Annabelle Lewis
wiley   +1 more source

Variational Approach of Marangoni Mixed Convection Boundary Layer Flow with Pade Technique

open access: yesJournal of Applied Fluid Mechanics, 2016
In this paper, Variational Iteration method with combining Pade approximation (Modified Variational Iteration Method-MVIM) is performed to Marangoni convection flow over the surface with buoyancy effects which is occurred gravity and external pressure ...
Murat Gubes, Galip Oturanc
doaj  

EMT‐associated bias in the Parsortix® system observed with pancreatic cancer cell lines

open access: yesMolecular Oncology, EarlyView.
The Parsortix® system was tested for CTC enrichment using pancreatic cancer cell lines with different EMT phenotypes. Spike‐in experiments showed lower recovery of mesenchymal‐like cells. This was confirmed with an EMT‐inducible breast cancer cell line.
Nele Vandenbussche   +8 more
wiley   +1 more source

Tumor clusters with divergent inflammation and human retroelement expression determine the clinical outcome of patients with serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Analysis of treatment‐naïve high‐grade serous ovarian carcinoma (HGSOC) and control tissues for ERVs, LINE‐1 (L1), inflammation, and immune checkpoints identified five clusters with diverse patient recurrence‐free survivals. An inflammation score was calculated and correlated with retroelement expression, where one novel cluster (Triple‐I) with high ...
Laura Glossner   +6 more
wiley   +1 more source

Triple Hierarchical Variational Inequalities, Systems of Variational Inequalities, and Fixed Point Problems

open access: yesMathematics, 2019
In this paper, we introduce a multiple hybrid implicit iteration method for finding a solution for a monotone variational inequality with a variational inequality constraint over the common solution set of a general system of variational inequalities ...
Lu-Chuan Ceng, Qing Yuan
doaj   +1 more source

An Indirect Method in the Calculus of Variations [PDF]

open access: yesTransactions of the American Mathematical Society, 1993
This article presents a new approach to the issue of the existence of solutions to the basic problem in the calculus of variations. The method is indirect, and applies to certain classes of of problems with slow or no growth, in addition to those satisfying the traditional coercivity condition.
openaire   +1 more source

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