Results 101 to 110 of about 332,833 (326)

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

open access: yesMolecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano   +6 more
wiley   +1 more source

Variational Approach of Marangoni Mixed Convection Boundary Layer Flow with Pade Technique

open access: yesJournal of Applied Fluid Mechanics, 2016
In this paper, Variational Iteration method with combining Pade approximation (Modified Variational Iteration Method-MVIM) is performed to Marangoni convection flow over the surface with buoyancy effects which is occurred gravity and external pressure ...
Murat Gubes, Galip Oturanc
doaj  

Simplified variational iteration method for solving ordinary differential equations and eigenvalue problems

open access: yesAdvances in Mechanical Engineering, 2016
A simplified variational iteration method is proposed to solve high-order homogeneous or nonhomogeneous linear ordinary differential equation and ordinary differential equation eigenvalue problems more efficiently and conveniently.
Chao Pan, Ruifu Zhang, Hao Luo, Hua Shen
doaj   +1 more source

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