Results 121 to 130 of about 13,356,537 (289)
Variational method for adiabatic compression of plasma with poloidal and toroidal rotation
A variational method is developed for adiabatic compression of plasma with both poloidal and toroidal ...
Pan LJ(潘良儒), L J Pan
core +1 more source
Circulating microRNA profiles distinguish nonmalignant Lynch syndrome from cancer‐associated Lynch syndrome, sporadic colorectal cancer, and healthy controls. Age‐stratified analysis reveals disease‐specific regulatory states, and a six‐miRNA panel shows concordant separation in an independent colorectal tissue cohort.
Ramadhani Salum Chambuso +5 more
wiley +1 more source
The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim +17 more
wiley +1 more source
Spatial heterogeneity of hotspot mutations and clonal relatedness in ovarian endometrioid carcinoma
Spatially resolved analysis revealed heterogeneous distributions of selected cancer‐associated mutations within ovarian endometrioid carcinomas. Shared mutations between paired endometrial and ovarian tumors supported clonal relatedness. These findings highlight the value of sampling multiple tumor regions when interpreting molecular profiles ...
Takahito Ashihara +10 more
wiley +1 more source
A Variational Method for Curve Extraction
We propose a functional for extracting curves between a list of possible endpoints, based on a discretization of a variational energy and Smirnov's decomposition theorem for vector fields. It is then used to design a bi-level minimization approach to automatically extract curves and 1D structures from an image, which is mostly unsupervised.
Arthaud, Majid +2 more
openaire +3 more sources
Tumour‐proximal deep serum proteomics identifies biomarkers associated with ovarian cancer
New biomarkers are needed for early ovarian cancer detection. Ovarian (tumour‐proximal) and peripheral vein serum from healthy women and patients with benign or malignant tumours underwent nanoparticle‐enriched deep proteomics. Ovarian serum yielded more protein identifications and revealed tumour‐reflective signatures.
Darren Lau +9 more
wiley +1 more source
Multiplicity of solutions for a quasilinear problem with supercritical growth
The multiplicity and concentration of positive solutions are established for the equation $$ -epsilon^{p}Delta_{p}u+V(z)|u|^{p-2}u=|u|^{q-2}u +lambda|u|^{s-2}u quadhbox{in }mathbb{R}^N, $$ where ...
Giovany M. Figueiredo
doaj
The impact of leukocyte‐associated RNA retention on platelet RNA‐based cancer detection
Platelets carry RNA signals that may help detect cancer, but platelet samples can also retain RNA from white blood cells. We found that this retained white blood cell signal did not significantly affect machine learning cancer classification, suggesting that the cancer‐related RNA signal in platelets is largely independent of leukocyte‐associated RNA ...
Michał Sieczczyński +12 more
wiley +1 more source
RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells
RoundMi is a workflow for rapid analysis of mitochondrial morphology in mitotic cells. By combining adaptive preprocessing with automated segmentation and quantification, it enables accurate measurements from single focal plane images, reducing acquisition time and computational demands while remaining compatible with high‐throughput fixed and live ...
Elmira Parvindokht Bararpour +2 more
wiley +1 more source
A variational method for image-based inference of internal stress in epithelial tissues. [PDF]
Noll N, Streichan SJ, Shraiman BI.
europepmc +1 more source

