Results 131 to 140 of about 30,988,225 (367)

Detecting homologous recombination deficiency for breast cancer through integrative analysis of genomic data

open access: yesMolecular Oncology, EarlyView.
This study develops a semi‐supervised classifier integrating multi‐genomic data (1404 training/5893 validation samples) to improve homologous recombination deficiency (HRD) detection in breast cancer. Our method demonstrates prognostic value and predicts chemotherapy/PARP inhibitor sensitivity in HRD+ tumours.
Rong Zhu   +12 more
wiley   +1 more source

Variational Approach of Marangoni Mixed Convection Boundary Layer Flow with Pade Technique

open access: yesJournal of Applied Fluid Mechanics, 2016
In this paper, Variational Iteration method with combining Pade approximation (Modified Variational Iteration Method-MVIM) is performed to Marangoni convection flow over the surface with buoyancy effects which is occurred gravity and external pressure ...
Murat Gubes, Galip Oturanc
doaj  

Local Fractional Laplace Variational Iteration Method for Fractal Vehicular Traffic Flow

open access: yesAdvances in Mathematical Physics, 2014
We discuss the line partial differential equations arising in fractal vehicular traffic flow. The nondifferentiable approximate solutions are obtained by using the local fractional Laplace variational iteration method, which is the coupling method of ...
Yang Li   +3 more
doaj   +1 more source

Weak convergence theorem for a class of split variational inequality problems and applications in a Hilbert space

open access: yesJournal of Inequalities and Applications, 2017
In this paper, we consider the algorithm proposed in recent years by Censor, Gibali and Reich, which solves split variational inequality problem, and Korpelevich’s extragradient method, which solves variational inequality problems. As our main result, we
Ming Tian, Bing-Nan Jiang
doaj   +1 more source

On the convergence of the variational iteration method

open access: yesJournal of Numerical Analysis and Approximation Theory, 2016
Convergence results are stated for the variational iteration method applied to solve an initial value problem for a system of ordinary differential equations.
openaire   +4 more sources

Evaluation of KRAS and NRAS mutations in metastatic colorectal cancer: an 8‐year study of 10 754 patients in Turkey

open access: yesMolecular Oncology, EarlyView.
This nationwide study evaluated KRAS and NRAS mutations in 10 754 Turkish patients with metastatic colorectal cancer. The results revealed a mutation frequency of 51.1%, with 46.6% having KRAS mutations, 4.5% having NRAS mutations, and 48.5% being wild‐type for both.
Gozde Kavgaci   +6 more
wiley   +1 more source

Landscape of BRAF transcript variants in human cancer

open access: yesMolecular Oncology, EarlyView.
We investigate the annotation of BRAF variants, focusing on protein‐coding BRAF‐220 (formerly BRAF‐reference) and BRAF‐204 (BRAF‐X1). The IsoWorm pipeline allows us to quantify these variants in human cancer, starting from RNA‐sequencing data. BRAF‐204 is more abundant than BRAF‐220 and impacts patient survival.
Maurizio S. Podda   +5 more
wiley   +1 more source

Loss of proton‐sensing GPR4 reduces tumor progression in mouse models of colon cancer

open access: yesMolecular Oncology, EarlyView.
G protein‐coupled receptor 4 (GPR4) is a pH‐sensing receptor activated by acidic pH. GPR4 expression is increased in patients with inflammatory bowel disease who are at high risk of developing colorectal cancer. In mouse models, loss of GPR4 attenuated tumor progression. This correlated with increased IL2 and natural killer cell activity.
Leonie Perren   +16 more
wiley   +1 more source

Asymptotic Methods for Solitary Solutions and Compactons

open access: yesAbstract and Applied Analysis, 2012
This paper is an elementary introduction to some new asymptotic methods for the search for the solitary solutions of nonlinear differential equations, nonlinear differential-difference equations, and nonlinear fractional differential equations ...
Ji-Huan He
doaj   +1 more source

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