Results 171 to 180 of about 328,225 (327)

Engineering tandem VHHs to target different epitopes to enhance antibody‐dependent cell‐mediated cytotoxicity

FEBS Open Bio, EarlyView.
Tandem VHH targeting distinct EGFR epitopes were engineered into a monovalent bispecific antibody (7D12‐EGA1‐Fc) with more potent ADCC without increasing affinity to EGFR. Structural modeling of 7D12‐EGA1‐Fc showed cross‐linking of separate EGFR domains to enhance CD16a engagement on NK cells.
Yuqiang Xu, Hao Jiang, Limin Chen, Fulai Zhou, Ying Jin, Mark L. Chiu   +5 more
wiley   +1 more source

Variational Method for Vibration Analysis of Elliptic Cylinders Reinforced with Functionally Graded Carbon Nanotubes. [PDF]

Materials (Basel)
Gong Q, Liu T, Teng Y, Ma B, Li X.
europepmc   +1 more source

Study of CZTS Nano-powder Synthesis by Hot Injection Method by Variation of Cu and Zn Concentrations

, 2016
Suresh Kumar, Vikash Kumar, Valdek Mikli, T. Varema, M. Altosaar, M. Grossberg   +5 more
openalex   +1 more source

Evaluation of in vitro toxicity of common phytochemicals included in weight loss supplements using 1H NMR spectroscopy

FEBS Open Bio, EarlyView.
We investigated the toxicity of 12 active compounds commonly found in herbal weight loss supplements (WLS) using human liver and colon cell models. Epigallocatechin‐3‐gallate was the only compound showing significant toxicity. Metabolic profiling revealed protein degradation, disrupted energy and lipid metabolism suggesting that the inclusion of EGCG ...
Emily C. Davies, Garth L. Maker, Ian F. Musgrave, Samantha Lodge   +3 more
wiley   +1 more source

Automatic Modeling Method of Support Behavior for Work Support System Based on Variational Deep Embedding–Generative Adversarial Networks

, 2020
Kohjiro Hashimoto, Tadashi Miyosawa, Tetsuyasu Yamada   +2 more
openalex   +1 more source

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

FEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon, Angéla Békesi, Latifa Kazzazy, Jázmin Mihály, Máté Varga, Beáta G. Vértessy, Kinga Nyíri   +6 more
wiley   +1 more source

Spatially and temporally high-order dynamic nonlinear variational multiscale methods for generalized Newtonian flows

Fabricio Byron Guerrero Ortiz, Ernesto Castillo, Felipe Galarce, Douglas R. Q. Pacheco   +3 more
openalex   +1 more source

Environmentally Friendly Quinolones Design for a Two-Way Choice between Biotoxicity and Genotoxicity through Double-Activity 3D-QSAR Model Coupled with the Variation Weighting Method [PDF]

, 2020
Peixuan Sun, Yuanyuan Zhao, Luze Yang, Zhixing Ren, Wenjin Zhao   +4 more
openalex   +1 more source

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

FEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

Uniform Convergence of Schwarz Method for Elliptic Quasi-Variational Inequalities Related to Impulse Control Problem [PDF]

, 2010
Mohamed Haiour, Salah Boulaaras
openalex   +1 more source