Results 181 to 190 of about 30,977,271 (369)

A non‐fluorescent immunohistochemistry method for measuring autophagy flux using MAP1LC3/LC3 and SQSTM1 as core markers

FEBS Open Bio, EarlyView.
We introduce an immunohistochemistry method to measure autophagy flux, highlighting the active degradation and recycling of cellular waste. This cost‐effective approach uses tissue samples to track key markers like LC3 and SQSTM1, revealing how cells maintain health or respond to diseases such as cancer. It bridges the gap between research and clinical
Shahla Shojaei, Amir Barzegar Behrooz, Marco Cordani, Mahmoud Aghaei, Negar Azarpira, Daniel J. Klionsky, Saeid Ghavami   +6 more
wiley   +1 more source

Comparative single‐cell transcriptomic profiling of patient‐derived renal carcinoma cells in cellular and animal models of kidney cancer

FEBS Open Bio, EarlyView.
We generated and characterized clear cell renal cell carcinoma models using the patient‐derived RCC243 cell line—including cell culture, orthotopic, and metastatic tumors—via single‐cell RNA‐sequencing for comparisons between models and patient tumor datasets.
Richard Huang, Lynn Kee, Alexander Gont, Jalna Meens, Fraser G. Ferens, Meredith S. Irwin, Laurie Ailles, Scott A. Yuzwa, Claire M. Robinson, Michael Ohh   +9 more
wiley   +1 more source

On subcellular distribution of the zinc finger 469 protein (ZNF469) and observed discrepancy in the localization of endogenous and overexpressed ZNF469

FEBS Open Bio, EarlyView.
ZNF469 regulates the expression of genes encoding extracellular matrix proteins. Endogenous ZNF469 is predominantly cytoplasmic, while in transfected cells, it forms aggregates reminiscent of biomolecular condensates, located mainly in the nucleus. These condensates exhibit overlapping staining with proteasomes and are also associated with the mitotic ...
Anne Elisabeth Christensen Mellgren, Ileana Cristea, Thomas Stevenson, Endy Spriet, Per Morten Knappskog, Stig Ove Bøe, Harald Kranz, Sushma N. Grellscheid, Eyvind Rødahl   +8 more
wiley   +1 more source

VAE-Var: Variational-Autoencoder-Enhanced Variational Assimilation [PDF]

arXiv
Data assimilation refers to a set of algorithms designed to compute the optimal estimate of a system's state by refining the prior prediction (known as background states) using observed data. Variational assimilation methods rely on the maximum likelihood approach to formulate a variational cost, with the optimal state estimate derived by minimizing ...
arxiv  

Closure to “Discussion of ‘A Short Method for the Evaluation of the Effect of Some Thermal-Cycle Variations on Steam-Turbine Heat Rates’” (1954, Trans. ASME, 76, pp. 663–664) [PDF]

, 1954
S. D. Fulton
openalex   +1 more source

Comparative study of adenosine 3′‐pyrophosphokinase domains of MuF polymorphic toxins

FEBS Open Bio, EarlyView.
With the ultimate goal of understanding the association of toxin‐immunity modules to temperate phages, we characterized toxins from three prophages and examined cross‐protection from immunity proteins. The toxins exhibit adenosine 3′‐pyrophosphokinase activity and are toxic in Escherichia coli.
Eloïse M. Paulet, Julia Bartoli, Atakan Kabtan, Chloé M. Piras, Audrey C. Tempier, Eric Cascales, Julie P. Viala   +6 more
wiley   +1 more source

Application of the complex Kohn variational method to attosecond spectroscopy. [PDF]

Phys Rev A (Coll Park), 2018
Douguet N, Schneider BI, Argenti L.
europepmc   +1 more source

Treatment of Ionized Impurity Scattering in Degenerate Semiconductors. Combination of the Variational and Perturbational Technique in the Partial-Wave Method [PDF]

, 1964
P. Csavinszky
openalex   +1 more source

Higher Modes of Non-Radial Oscillations of Stars by Variational Methods [PDF]

, 1967
AL Andrew
openalex   +1 more source

Variational Method for Vibration Analysis of Elliptic Cylinders Reinforced with Functionally Graded Carbon Nanotubes. [PDF]

Materials (Basel)
Gong Q, Liu T, Teng Y, Ma B, Li X.
europepmc   +1 more source