Results 111 to 120 of about 50,436 (310)
Molecular Oncology, EarlyView.Detection of extrachromosomal circular DNA (eccDNA) in plasma samples from EGFR‐mutated non‐small cell lung cancer patients. Plasma was collected before and during treatment with the EGFR‐tyrosine kinase inhibitor osimertinib. Plasma eccDNA was detected in all cancer samples, and the presence of the EGFR gene on eccDNA serves as a potential biomarker ...
Simone Stensgaard +5 more
wiley +1 more source
Parameter-Free Selective Segmentation With Convex Variational Methods. [PDF]
IEEE Trans Image Process, 2019 Spencer J, Chen K, Duan J.
europepmc +1 more source
THE STUDY OF IMPERFECT COMPLEXES. PART I. CALORIMETRIC STUDY OF COMPLEXES BY JOB'S METHOD OF CONTINUED VARIATION [PDF]
, 1948 SUSHIL KUMAR SIDDHANTA
openalex +1 more source
Survivin and Aurora Kinase A control cell fate decisions during mitosis
Molecular Oncology, EarlyView.Aurora A interacts with survivin during mitosis and regulates its centromeric role. Loss of Aurora A activity mislocalises survivin, the CPC and BubR1, leading to disruption of the spindle checkpoint and triggering premature mitotic exit, which we refer to as ‘mitotic slippage’.
Hana Abdelkabir +2 more
wiley +1 more source
Molecular Oncology, EarlyView.A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.
Liqun He +8 more
wiley +1 more source
A discontinuous problem involving the p-Laplacian operator and critical exponent in $mathbb{R}^N$
Electronic Journal of Differential Equations, 2003 Using convex analysis, we establish the existence of at least two nonnegative solutions for the quasilinear problem $$ -Delta_{p}u=H(u-a)u^{p^*-1} +lambda h(x)quadhbox{in }mathbb{R}^N $$ where $Delta_{p}u$ is the $p$-Laplacian operator, $H$ is the ...
Claudianor Oliveira Alves +1 more
doaj
A guide to reactive oxygen species in tumour hypoxia: measurement and therapeutic implications
Molecular Oncology, EarlyView.Hypoxia reshapes tumour redox landscapes by altering compartmental ROS production (mitochondria, NOX, ER, peroxisomes). Accurate interpretation requires oxygen‐contextualised measurement (live biosensors, chemical probes, EPR, LC–MS) and awareness of artefacts (reoxygenation, probe specificity).
Lina Hacker +3 more
wiley +1 more source
Existence of solutions to nonlocal elliptic equations with discontinuous terms
Electronic Journal of Differential Equations, 2012 In this article, we study the existence of nonnegative solutions for the elliptic partial differential equation $$displaylines{ -[M(|u|^{p}_{1,p})]^{1,p}Delta_{p}u = f(x,u) quadhbox{in } Omega , cr u = 0 quadhbox{on } partialOmega , }$$ where ...
Francisco Julio S. A. Correa +1 more
doaj
Closure to “Discussion of ‘A Short Method for the Evaluation of the Effect of Some Thermal-Cycle Variations on Steam-Turbine Heat Rates’” (1954, Trans. ASME, 76, pp. 663–664) [PDF]
, 1954 S. D. Fulton
openalex +1 more source
Molecular Oncology, EarlyView.Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra +10 more
wiley +1 more source