Results 121 to 130 of about 31,755,712 (367)
Tryptophan metabolite atlas uncovers organ, age, and sex‐specific variations
FEBS Open Bio, EarlyView.Tryptophan metabolites were analyzed across twelve organs, the central nervous system, and serum in male and female mice at three life stages. We found tissue‐, sex‐, and age‐specific differences, including increased indole‐3‐pyruvate and kynurenine in aging males.
Lizbeth Perez‐Castro +8 more
wiley +1 more source
Absolute Value Variational Inequalities and Dynamical Systems
International Journal of Analysis and Applications, 2020 In this paper, we consider the absolute value variational inequalities. We propose and analyze the projected dynamical system associated with absolute value variational inequalities by using the projection method.
Safeera Batool +2 more
doaj
On a class of semilinear elliptic problems near critical growth
International Journal of Mathematics and Mathematical Sciences, 1998 We use Minimax Methods and explore compact embedddings in the context of Orlicz and Orlicz-Sobolev spaces to get existence of weak solutions on a class of semilinear elliptic equations with nonlinearities near critical growth. We consider both biharmonic
J. V. Goncalves, S. Meira
doaj +1 more source
FEBS Open Bio, EarlyView.CAF‐mediated immunosuppression in ovarian cancer is driven by IDO1, reducing T‐cell function. Inhibiting IDO1 restores T‐cell proliferation and cytotoxicity, increases cancer cell apoptosis, and may help overcome CAF‐induced immune suppression in high‐grade serous ovarian cancer. Targeting IDO1 may improve antitumor immunity.
Hyewon Lee +3 more
wiley +1 more source
Variational Networks: An Optimal Control Approach to Early Stopping Variational Methods for Image Restoration. [PDF]
J Math Imaging Vis, 2020 Effland A, Kobler E, Kunisch K, Pock T.
europepmc +1 more source
New iterative regularization methods for solving split variational inclusion problems
, 2021 Dang Van Hieu +2 more
openalex +1 more source
An Introduction to Variational Methods for Graphical Models
Machine-mediated learning, 1999 Michael I. Jordan +3 more
semanticscholar +1 more source
A general model for analysis of linear and hyperbolic enzyme inhibition mechanisms
FEBS Open Bio, EarlyView.We developed a general enzyme kinetic model that integrates these six basic inhibition mechanism onto a single one. From this model, we deduced a general enzyme kinetic equation that through modulation of simple parameters, γ (the relative inhibitor affinity for two binding sites) and β (the reactivity of the enzyme–substrate–inhibitor complex), is ...
Rafael S. Chagas, Sandro R. Marana
wiley +1 more source
Thrombolytic proteins profiling: High‐throughput activity, selectivity, and resistance assays
FEBS Open Bio, EarlyView.We present optimized biochemical protocols for evaluating thrombolytic proteins, enabling rapid and robust screening of enzymatic activity, inhibition resistance, and fibrin affinity, stimulation, and selectivity. The outcome translates to key clinical indicators such as biological half‐life and bleeding risk. These assays streamline the development of
Martin Toul +3 more
wiley +1 more source