Results 111 to 120 of about 287,859 (234)
FEBS Open Bio, EarlyView.Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley +1 more source
Nontrivial solutions for noncooperative elliptic systems at resonance
Electronic Journal of Differential Equations, 2001 In this article we establish the existence of a nonzero solution for variational noncooperative elliptic systems under Dirichlet boundary conditions and a resonant condition at infinity.
Elves A. B. Silva
doaj
FEBS Open Bio, EarlyView.A tri‐culture of iPSC‐derived neurons, astrocytes, and microglia treated with ferroptosis inducers as an Induced ferroptosis model was characterized by scRNA‐seq, cell survival, and cytokine release assays. This analysis revealed diverse microglial transcriptomic changes, indicating that the system captures key aspects of the complex cellular ...
Hongmei Lisa Li +6 more
wiley +1 more source
Existence and nonexistence of nontrivial solutions for Choquard type equations
Electronic Journal of Differential Equations, 2016 In this article, we consider the nonlocal problem $$ -\Delta u+u=q(x)\Big(\int_{\mathbb{R}^N}\frac{q(y)|u(y)|^p}{|x-y|^{N-\alpha}}dy \Big)|u|^{p-2}u,\quad x\in \mathbb{R}^N, $$ where $N\geq 3$, $\alpha\in (0,N)$, $\frac{N+\alpha}{N}
Tao Wang
doaj
FEBS Open Bio, EarlyView.Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei +3 more
wiley +1 more source
FEBS Open Bio, EarlyView.In this study, we developed a deep learning method for mitotic figure counting in H&E‐stained whole‐slide images and evaluated its prognostic impact in 13 external validation cohorts from seven different cancer types. Patients with more mitotic figures per mm2 had significantly worse patient outcome in all the studied cancer types except colorectal ...
Joakim Kalsnes +32 more
wiley +1 more source
FEBS Open Bio, EarlyView.Amino acids sequence of two different proteins with the same sequence (chameleon sequence—black boxes) represent in 3D structure of the proteins different secondary structures: HHHH—helical and BBB—Beta‐structural. The chains folded in water environment adopt different III‐order structures in which the chameleon fragments appear to adopt similar status
Irena Roterman +4 more
wiley +1 more source
On Two Iterative Methods for Mixed Monotone Variational Inequalities
Fixed Point Theory and Applications, 2010 A mixed monotone variational inequality (MMVI) problem in a Hilbert space is formulated to find a point such that for all , where is a monotone operator and is a proper, convex, and lower semicontinuous function on . Iterative algorithms are
Xu Hong-Kun, Lu Xiwen, Yin Ximing
doaj
FEBS Open Bio, EarlyView.ERα splice variant ERα∆7 lacks the C‐terminus, and its expression may change phenotypes of breast cancers. Our results showed that ERα∆7 is found in the luminal A subtype, and elevated ERα∆7 levels are linked to improved cell survival with lower proliferation and migration.
Long Wai Tsui +10 more
wiley +1 more source
Variational Methods and Critical Point Theory 2013
Abstract and Applied Analysis, 2013 M. Victoria Otero-Espinar +3 more
doaj +1 more source