Results 151 to 160 of about 292,354 (329)

Existence and concentration of positive bound states for Schrodinger-Poisson systems with potential functions

open access: yesElectronic Journal of Differential Equations, 2015
In this article we study the existence and concentration behavior of bound states for a nonlinear Schrodinger-Poisson system with a parameter $\varepsilon>0$.
Patricia L. Cunha
doaj  

Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology

open access: yesMolecular Oncology, EarlyView.
Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts   +8 more
wiley   +1 more source

Homoclinic solutions for a class of second-order Hamiltonian systems with locally defined potentials

open access: yesElectronic Journal of Differential Equations, 2017
In this article, we establish sufficient conditions for the existence of homoclinic solutions for a class of second-order Hamiltonian systems $$ \ddot u(t)-L(t)u(t)+\nabla W\bigl(t,u(t)\bigr)=f(t), $$ where L(t) is a positive definite symmetric ...
Xiang Lv
doaj  

Adenosine‐to‐inosine editing of miR‐200b‐3p is associated with the progression of high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira   +14 more
wiley   +1 more source

Existence of standing waves for Schrodinger equations involving the fractional Laplacian

open access: yesElectronic Journal of Differential Equations, 2017
We study a class of fractional Schrodinger equations of the form $$ \varepsilon^{2\alpha}(-\Delta)^\alpha u+ V(x)u = f(x,u) \quad\text{in } \mathbb{R}^N, $$ where $\varepsilon$ is a positive parameter, $0 < \alpha < 1$, $2\alpha < N$, $(-\Delta ...
Everaldo S. de Medeiros   +2 more
doaj  

Investigating the cell of origin and novel molecular targets in Merkel cell carcinoma: a historic misnomer

open access: yesMolecular Oncology, EarlyView.
This study indicates that Merkel cell carcinoma (MCC) does not originate from Merkel cells, and identifies gene, protein & cellular expression of immune‐linked and neuroendocrine markers in primary and metastatic Merkel cell carcinoma (MCC) tumor samples, linked to Merkel cell polyomavirus (MCPyV) status, with enrichment of B‐cell and other immune cell
Richie Jeremian   +10 more
wiley   +1 more source

Multiple solutions for perturbed non-local fractional Laplacian equations

open access: yesElectronic Journal of Differential Equations, 2013
In article we consider problems modeled by the non-local fractional Laplacian equation $$\displaylines{ (-\Delta)^s u=\lambda f(x,u)+\mu g(x,u) \quad\text{in } \Omega\cr u=0 \quad\text{in } \mathbb{R}^n\setminus \Omega, }$$ where $s\in (0,1)$ is ...
Massimiliano Ferrara   +2 more
doaj  

Understanding and measuring mechanical signals in the tumor stroma

open access: yesFEBS Open Bio, EarlyView.
This review discusses cancer‐associated fibroblast subtypes and their functions, particularly in relation to extracellular matrix production, as well as the development of 3D models to study tumor stroma mechanics in vitro. Several quantitative techniques to measure tissue mechanical properties are also described, to emphasize the diagnostic and ...
Fàtima de la Jara Ortiz   +3 more
wiley   +1 more source

Variational Methods and Critical Point Theory 2013

open access: yesAbstract and Applied Analysis, 2013
M. Victoria Otero-Espinar   +3 more
doaj   +1 more source

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