Results 161 to 170 of about 57,276 (313)

The heteroclinic connection problem for general double-well potentials

open access: yes, 2014
By variational methods, we provide a simple proof of existence of a heteroclinic orbit to a second order Hamiltonian ODE that connects the two global minima of a double-well potential.
Sourdis, Christos
core  

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

open access: yesFEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young   +7 more
wiley   +1 more source

Including Social Nash Equilibria in Abstract Economies [PDF]

open access: yes
We consider quasi-variational problems (variational problems having constraint sets depending on their own solutions) which appear in concrete economic models such as social and economic networks, financial derivative models, transportation network ...
Jacqueline Morgan, M. Beatrice Lignola
core  

On the convergence of combined relaxation methods for variational inequalities

open access: yes, 2020
A general approach to constructing iterative methods that solve variational inequalities under mild assumptions is proposed. It is based on combining and modifying ideas contained in various relaxation methods.
Konnov I.
core  

Early‐life high‐fat diet exposure increases Achilles tendon stiffness and induces transcriptomic alterations

open access: yesFEBS Open Bio, EarlyView.
Early‐life exposure to a high‐fat diet altered intact Achilles tendons in rat offspring, making them thinner, stiffer, and molecularly distinct even without injury. These findings suggest that developmental high‐fat diet exposure may impair tendon quality and increase susceptibility to mechanical overload or tendon injury later in life.
Heyong Yin   +3 more
wiley   +1 more source

Bayesian Regression Methods for Crossing Survival Curves

open access: yes, 2009
In survival data analysis, the proportional hazards (PH), accelerated failure time (AFT), and proportional odds (PO) models are commonly used semiparametric models for the comparison of survivability in subjects.
DiCasoli, Carl Matthew
core  

RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells

open access: yesFEBS Open Bio, EarlyView.
RoundMi is a workflow for rapid analysis of mitochondrial morphology in mitotic cells. By combining adaptive preprocessing with automated segmentation and quantification, it enables accurate measurements from single focal plane images, reducing acquisition time and computational demands while remaining compatible with high‐throughput fixed and live ...
Elmira Parvindokht Bararpour   +2 more
wiley   +1 more source

Mixed effect estimation in deep compartment models: Variational methods outperform first-order approximations. [PDF]

open access: yesJ Pharmacokinet Pharmacodyn
Janssen A   +4 more
europepmc   +1 more source

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