Results 81 to 90 of about 862 (204)
Supercritical Semi-Linear Elliptic Problems Using Variational Principles [PDF]
The thesis investigates the use of variational methods to study elliptic partial differential equations (PDEs) with supercritical nonlinearities. By focusing on convex subsets of a Banach space, the research overcomes compactness issues typically ...
Sadeghi Kenarsari, Banafsheh
core +2 more sources
PDE4D and PDE3B orchestrate distinct cAMP microdomains in 3T3‐L1 adipocytes
British Journal of Pharmacology, EarlyView.Basal conditions: •Ins/PDE3B lowers cytoplasmic cAMP (cyt‐cAMP) without affecting plasma membrane cAMP (pm‐cAMP). •Insulin decreases lipid droplet cAMP (LD‐cAMP) independent of PDE3B. •FGF1/PDE4D modestly reduces both cyt‐ and pm‐cAMP, while PDE4D alone can modulate LD‐cAMP. ISO stimulation: •Ins/PDE3B has minimal impact on cyt‐cAMP.
Johannes Krier +9 more
wiley +1 more source
British Journal of Pharmacology, EarlyView.Background and Purpose Metabolic dysfunction‐associated steatohepatitis (MASH) is linked to activation of hepatic stellate cells (HSCs) to α‐smooth muscle actin–positive myofibroblasts that produce collagen and proinflammatory cytokines. Quiescent HSCs express the NO‐cGMP signalling axis.
Krithika Rajeeth +14 more
wiley +1 more source
Least-squares finite element methods and algebraic multigrid solvers for linear hyperbolic PDEs [PDF]
, 2008 . Least-squares finite element methods (LSFEMs) for scalar linear partial differential equations (PDEs) of hyperbolic type are studied. The space of admissible boundary data is identified precisely, and a trace theorem and a Poincaré inequality are ...
Luke Olson +3 more
core
Computing Skinning Weights via Convex Duality
Computer Graphics Forum, EarlyView.We present an alternate optimization method to compute bounded biharmonic skinning weights. Our method relies on a dual formulation, which can be optimized with a nonnegative linear least squares setup. Abstract We study the problem of optimising for skinning weights through the lens of convex duality.
J. Solomon, O. Stein
wiley +1 more source
SDFs from Unoriented Point Clouds using Neural Variational Heat Distances
Computer Graphics Forum, EarlyView.We propose a novel variational approach for computing neural Signed Distance Fields (SDF) from unoriented point clouds. We first compute a small time step of heat flow (middle) and then use its gradient directions to solve for a neural SDF (right). Abstract We propose a novel variational approach for computing neural Signed Distance Fields (SDF) from ...
Samuel Weidemaier +5 more
wiley +1 more source
Controllable Intrinsic Surface Pattern Generation Using Slime Mold Simulations
Computer Graphics Forum, EarlyView.Abstract Surface‐based pattern simulations have proven valuable for texture design and scientific visualization, but existing methods face several limitations. Most simulations either target a narrow range of pattern types (e.g. spots, branching) or support a broad range of patterns at the cost of time‐consuming parameter tuning.
Jeffrey Layton +2 more
wiley +1 more source
Interpolated Adaptive Linear Reduced Order Modeling for Deformation Dynamics
Computer Graphics Forum, EarlyView.Abstract Linear reduced‐order modeling (ROM) is widely used for efficient simulation of deformation dynamics, but its accuracy is often limited by the fixed linearization of the reduced mapping. We propose a new adaptive strategy for linear ROM that allows the reduced mapping to vary dynamically in response to the evolving deformation state ...
Y. Tao, M. Chiaramonte, P. Fernandez
wiley +1 more source
Enhancing CRISPR‐Cas12a base editing in plants with LbCas12a variants and introns
Journal of Integrative Plant Biology, EarlyView.Intron optimization of LbCas12a‐RRV improves cytosine and adenine base editing efficiency in plants, supports multiplexed and double‐strand break‐free genome modification, and expands precise genome engineering tools for crop breeding and plant functional research. ABSTRACT Cytosine base editors (CBEs) and adenine base editors (ABEs) are powerful tools
Yanhao Cheng +5 more
wiley +1 more source
Variational and differential models for shape modeling [PDF]
The spread of new technologies led to a crucial role for the modeling of 3D objects, in particular for shape modeling, in a variety of applications, such as architecture, cultural heritage, industrial design, computer graphics, 3D radar scanning and ...
Recupero, Giuseppe Antonio <1998>
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