Results 51 to 60 of about 2,013,078 (286)

Variational principles for integrals [PDF]

open access: yesJournal of Computational Physics, 1969
We consider the problem of approximating integrals of the form ∫ 1W where W may be a simple (e.g. polynomial) form in the integration variables. A variational expression is given which approximates this integral in terms of integrals of W with suitably chosen trial functions.
openaire   +3 more sources

Variational Time Integrators in Computational Solid Mechanics [PDF]

open access: yes, 2003
This thesis develops the theory and implementation of variational integrators for computational solid mechanics problems, and to some extent, for fluid mechanics problems as well.
Lew, Adrián José
core   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

open access: yesFEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Speed-gradient Entropy Principle for Nonstationary Processes

open access: yesEntropy, 2008
The speed-gradient variational principle (SG-principle) for nonstationary far from equilibrium systems is formulated and illustrated by examples. The SG-model of transient (relaxation) dynamics for systems of a finite number of particles based on maximum
Alexander Fradkov
doaj   +1 more source

Epigenetic reprogramming of lineage switching in cancer

open access: yesFEBS Letters, EarlyView.
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı   +4 more
wiley   +1 more source

On Ekeland’s variational principle [PDF]

open access: yesJournal of Fixed Point Theory and Applications, 2011
For proper lower semi-continuous functionals bounded below which do not increase upon polarization, an improved version of Ekeland's variational principle can be formulated in Banach spaces, which provides almost symmetric points.
openaire   +4 more sources

Artificial molecular machines and motors—Design and control of nanoscale motion

open access: yesFEBS Letters, EarlyView.
Molecules are constantly moving because of thermal fluctuations, but random motion alone cannot be exploited to perform directional tasks. Artificial molecular machines use chemical, electrical, or light energy to bias this motion. Molecular shuttles, rotary motors, and supramolecular pumps illustrate how nanoscale movement can be controlled and ...
Leonardo Andreoni, Alberto Credi
wiley   +1 more source

Metamaterial Acoustics on the (2 + 1)D Einstein Cylinder

open access: yesMathematics, 2021
The Einstein cylinder is the first cosmological model for our universe in modern history. Its geometry not only describes a static universe—a universe being invariant under time reversal—but it is also the prototype for a maximally symmetric spacetime ...
Michael M. Tung
doaj   +1 more source

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

open access: yesMolecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner   +14 more
wiley   +1 more source

Zasady wariacyjne a ich teleologiczna interpretacja

open access: yesZagadnienia Filozoficzne w Nauce, 2008
In this paper the problem of philosophical interpretation of variational principles is under investigation. The difference between differential and integral principles is presented and the history of various formulations of integral principles is ...
Dominika Domaciuk
doaj  

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