Results 101 to 110 of about 3,488,652 (310)
Decadal-centennial scale monsoon variations in the Arabian Sea during the Early Holocene [PDF]
An essential prerequisite for the prediction of future climate change due to anthropogenic input is an understanding of the natural processes that control Earth's climate on timescales comparable to human-lifespan. The Early Holocene period was chosen to
Ganssen, G. +11 more
core +1 more source
Evaluation of oryzalin-induced putative polyploids of Jasminum sambac cv. Ramanathapuram Gundumalli
The aim of the research was to create genetic variations in Jasminum sambac using oryzalin as a polyploidizing agent. Rooted stem cuttings of J. sambac were treated with oryzalin (0.005, 0.01 and 0.05%) and their vegetative and flowering parameters were
S Vishnupandi +4 more
doaj +1 more source
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi +5 more
wiley +1 more source
La beauté est dans la rue [PDF]
Le nouveau Variations est arrivé, il a pour titre : La beauté est dans la rue. Pour cette publication, il ne s’agit pas de faire un énième opuscule sur Mai 68. Il ne s’agit ni d’encenser, ni d’exhumer des « lendemains qui ont chanté ».
core +1 more source
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
wiley +1 more source
Désintégrer Heidegger / den Heidegger zetrümmern.
L'idée de "désintégrer Heidegger" correspond au projet de cercle de lecture consacré aux écrits du philosophe nazi, et que Walter Benjamin envisage en 1930 en dialogue avec Bertold Brecht qu'il fréquente pendant son exil parisien (cf.
Neumann, Alexander
core
Calpain small subunit homodimerization is robust and calcium‐independent
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
The research exposition consists of a case study in non-human phenomenology. The topic of the study derives from Jakob von Uexküll´s (1864–1944) classic ecological studies on the “lifeworld” (Umwelt) of animals, the focus being on the lifeworld of a tick.
openaire +1 more source

