Results 111 to 120 of about 3,488,652 (310)

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Genetic variability for yield and related traits among wild accessions of cowpea and cross-compatibility with cultivated accessions

open access: yesAgricultura Tropica et Subtropica
Cowpea is an important legume, and its wild relatives could be reliable sources of favorable alleles for genetic diversity and improvement of important traits.
Olayiwola Richard Oluseyi   +3 more
doaj   +1 more source

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

open access: yesFEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz   +11 more
wiley   +1 more source

Calculus of variations: A differential form approach

open access: yes
We study integrals of the form integral(Omega) f(d omega(1), ..., d omega(m)), where m >= 1 is a given integer, 1 R is a continuous function. We introduce the appropriate notions of convexity, namely vectorial ext.
Sil, Swarnendu
core   +1 more source

Variation in Variation Measurement: A Mapping Review of Methods to Study Clinical Variation

open access: yesJournal of Evaluation in Clinical Practice
ABSTRACT Rationale Variation in health care delivery exists at many levels (e.g., provider, practice, system) and can often be explained by various factors at each level. Understanding clinical variation presents an opportunity to improve the value of health care by identifying low‐value care ...
Amity E. Quinn   +11 more
openaire   +2 more sources

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

open access: yesFEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

PERONEUS TERTIUS: VARIATIONS AND CLINICAL APPLICATIONS IN GUJARATI POPULATION

open access: yesNational Journal of Medical Research, 2021
Introduction: Peroneus tertius (PT) is a muscle of the anterior compartment of the leg. The PT muscle originates from the anterior surface of the fibula and the interosseous membrane and inserts into the medial side of the dorsal region of the fifth ...
Rashvaita K Patel, Vipul D Patel
doaj  

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

open access: yesFEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure   +3 more
wiley   +1 more source

Pour une imagination radicale

open access: yes, 2013
A l’occasion de la parution en français du livre de Nancy Fraser, Le féminisme en mouvements, introduit par Estelle Ferrarese (La Découverte, 2012), nous retrouvons la philosophe new-yorkaise dix ans après un premier entretien publié dans Variations ...
Fraser, Nancy   +3 more
core   +1 more source

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