Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
FEBS Letters, EarlyView.EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
Variations in Acetabular Offset Between the Preoperative Plan (mediCAD<sup>®</sup>) and Postoperative Radiographic Measurements: an overlooked source of error that affects restoration of global offset after THA. [PDF]
SICOT JMatray A +5 more
europepmc +1 more source
Emerging experimental and computational methods for studying redox‐regulated structural transitions
FEBS Letters, EarlyView.Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
A recording and performer's analysis of Partita-variations for piano solo by George Rochberg
, 2012 The purpose of this document is to provide a recording and a performer’s analysis of the piano work titled Partita-Variations by American composer George Rochberg, as well as to provide an accessible guide for the pianist in understanding his role as a ...
Chin, Yu-Ching
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Tidal tomography reveals a thermal anomaly beneath Mars's crustal dichotomy. [PDF]
NatureBerne A +13 more
europepmc +1 more source
Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding
FEBS Letters, EarlyView.In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança +2 more
wiley +1 more source
Anatomical variation of the profunda femoris artery: High origin and complete overlap of femoral vessels - A rare case report. [PDF]
Medicine (Baltimore)Harizanova Z +3 more
europepmc +1 more source
Translophagy—A potential link between autophagy impairment and translational errors
FEBS Letters, EarlyView.Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk +11 more
wiley +1 more source
Donald Grantham's Fantasy variations
, 2003 textDonald Grantham’s composition, Fantasy Variations, started its life as a work for two pianos, commissioned by the Race/Groves Duo. The primary motivic material is based on George Gershwin’s Second Prelude from his Piano Preludes, Book 1.
Williams, Kraig Alan
core
A partially duplicated left ovarian vein bisected by the left renal artery: Hypothesized embryologic origins and clinical implications. [PDF]
Urol Case RepStoecker A +7 more
europepmc +1 more source