Results 11 to 20 of about 217,756 (210)

Gastric Variceal Bleeding in the Elderly [PDF]

International Journal of Gerontology, 2012
Background: Upper gastrointestinal bleeding of all causes has a higher morbidity and mortality in older patients compared with younger patients. We retrospectively studied gastric variceal bleeding in older patients and compared the complications and ...
Horng-Yuan Wang, Ming-Jen Chen, Ching-Chung Lin, Chih-Jen Chen, Chia-Yuan Liu, Tsang-En Wang, Fang-Ju Sun, Shee-Chan Lin, Shou-Chuan Shih   +8 more
doaj   +2 more sources

Variceal band ligation in the prevention of variceal bleeding: A multicenter trial

The Saudi Journal of Gastroenterology, 2011
Background/Aim: Variceal bleeding is a life-threatening complication of portal hypertension with a high probability of recurrence. Treatment to prevent first bleeding or rebleeding is mandatory. The study has been aimed at investigating the effectiveness
Asma Ouakaa-Kchaou, Jamel Kharrat, Khaoula Mir, Boussourra Houda, Nabil Abdelli, Salem Ajmi, Msaddek Azzouz, Hatem Ben Abdallah, Nabyl Ben Mami, Slim Bouzaidi, Sofiene Chouaib, Lamia Golli, Wissem Melki, Taoufik Najjar, Hammouda Saffar, Najet Belhadj, Abdeljabbar Ghorbel   +16 more
doaj   +2 more sources

Circulating TREM2 as a noninvasive diagnostic biomarker for NASH in patients with elevated liver stiffness

Hepatology, EarlyView., 2022
Abstract Background and Aims Reliable noninvasive biomarkers are an unmet clinical need for the diagnosis of NASH. This study investigates the diagnostic accuracy of the circulating triggering receptor expressed on myeloid cells 2 (plasma TREM2) as a biomarker for NASH in patients with NAFLD and elevated liver stiffness.
Vineesh Indira Chandran, Charlotte Wilhelmina Wernberg, Mette Munk Lauridsen, Maria Kløjgaard Skytthe, Sofie Marchsteiner Bendixen, Frederik Tibert Larsen, Camilla Dalby Hansen, Lea Ladegaard Grønkjær, Majken Storm Siersbæk, Tina Di Caterino, Sönke Detlefsen, Holger Jon Møller, Lars Grøntved, Kim Ravnskjaer, Søren Kragh Moestrup, Maja Sofie Thiele, Aleksander Krag, Jonas Heilskov Graversen   +17 more
wiley   +1 more source

Targeted decrease of portal hepatic pressure gradient improves ascites control after TIPS

Hepatology, EarlyView., 2022
The river diagram demonstrates that after transjugular intrahepatic portosystemic shunt insertion (TIPS) the majority of patients without ascites and 50% of the patients with ascites detectable at ultrasound, show the best response in the long term follow‐up.
Alexander Queck, Louise Schwierz, Wenyi Gu, Philip G. Ferstl, Christian Jansen, Frank E. Uschner, Michael Praktiknjo, Johannes Chang, Maximilian J. Brol, Filippo Schepis, Manuela Merli, Christian P. Strassburg, Jennifer Lehmann, Carsten Meyer, Jonel Trebicka   +14 more
wiley   +1 more source

Genetic predisposition to porto‐sinusoidal vascular disorder: A functional genomic‐based, multigenerational family study

Hepatology, EarlyView., 2022
A deleterious variant of FCHSD1 results in mTOR pathway overactivation and may cause porto‐sinusoidal vascular disorder (PSVD). The pedigree of the family demonstrated an autosomal dominant disease with variable expressivity. Whole‐genome sequencing and Sanger sequencing both validated the existence of the FCHSD1 variant and the heterozygosity of c ...
Jingxuan Shan, André Megarbane, Aziz Chouchane, Deepak Karthik, Ramzi Temanni, Atilio Reyes Romero, Huiying Hua, Chun Pan, Xixi Chen, Murugan Subramanian, Chadi Saad, Hamdi Mbarek, Cybel Mehawej, Eliane Chouery, Sirin W. Abuaqel, Alexander Dömling, Sami Remadi, Cesar Yaghi, Pu Li, Lotfi Chouchane   +19 more
wiley   +1 more source

Health disparities in chronic liver disease

Hepatology, EarlyView., 2022
Abstract The syndemic of hazardous alcohol consumption, opioid use, and obesity has led to important changes in liver disease epidemiology that have exacerbated health disparities. Health disparities occur when plausibly avoidable health differences are experienced by socially disadvantaged populations.
Ani Kardashian, Marina Serper, Norah Terrault, Lauren D. Nephew   +3 more
wiley   +1 more source

Janus kinase 2 inhibition by pacritinib as potential therapeutic target for liver fibrosis

Hepatology, EarlyView., 2022
Diagram of the activation of the profibrotic and procontractile Janus kinase 2 (JAK2)/Ras homolog family member A/Rho‐kinase pathway and the inhibition of phosphorylated JAK2 by pacritinib to inhibit hepatic stellate cell activity. Abstract Background and Aims Janus kinase 2 (JAK2) signaling is increased in human and experimental liver fibrosis with ...
Sandra Torres, Cristina Ortiz, Nadine Bachtler, Wenyi Gu, Leon D. Grünewald, Nico Kraus, Robert Schierwagen, Christoph Hieber, Caroline Meier, Olaf Tyc, Maximilian Joseph Brol, Frank Erhard Uschner, Bart Nijmeijer, Christoph Welsch, Marie‐Luise Berres, Carmen Garcia‐Ruiz, Jose Carlos Fernandez‐Checa, Christian Trautwein, Thomas J. Vogl, Stefan Zeuzem, Jonel Trebicka, Sabine Klein   +21 more
wiley   +1 more source

Endoscopic Thrombin Injection for Gastric Variceal Bleeding: A Systematic Review and Meta-Analysis of Observational and Trial Data. [PDF]

DEN Open
ABSTRACT Objective The safety of endoscopic thrombin injection (ETI) for treating the bleeding of gastric varix (GV) in patients with portal hypertension requires further evaluation. This meta‐analysis systematically reviews the available evidence on the efficacy and safety of ETI for GV bleeding.
Xu W, Zhan DQ, Wang RL, Jin S, Ding HG.
europepmc   +2 more sources

A Fibreoptic Endoscopic Study of Upper Gastrointestinal Bleeding at Bugando Medical Centre in Northwestern Tanzania: a Retrospective Review of 240 Cases. [PDF]

, 2012
Upper gastrointestinal (GI) bleeding is recognized as a common and potentially life-threatening abdominal emergency that needs a prompt assessment and aggressive emergency treatment.
Wolfgang Scheppach, Koy Mheta, Kabangila Rodrick, Mirambo, M, Rodrick Kabangila, Scheppach Wolfgang, Phillipo L Chalya, Mirambo, Mariam, Chalya Phillipo L, Liwa, Anthony, Jaka Hyasinta, Mchembe Mabula D, Jaka, H., McHembe, M.D., Koy, Mheta, Scheppach, W., Mkongo Eliasa, Jaka, Hyasinta, Liwa Anthony, Eliasa Mkongo, Mirambo Mariam, Mabula D Mchembe, Mariam Mirambo, Liwa, A., Anthony Liwa, Scheppach, Wolfgang, Chalya, Phillipo L, Chalya, P.L., McHembe, Mabula D, Kabangila, Rodrick, Koy, M., Hyasinta Jaka, Mheta Koy, Mkongo, E., Kabangila, R., Mkongo, Eliasa   +35 more
core   +1 more source

Effects of Early Placement of Transjugular Portosystemic Shunts in Patients With High-Risk Acute Variceal Bleeding: a Meta-analysis of Individual Patient Data

, 2021
Background & aims: Compared with drugs plus endoscopy, placement of transjugular portosystemic shunt within 72 hours of admission to the hospital (early or preventive transjugular intrahepatic portosystemic shunt [TIPS], also called preemptive TIPS ...
Nicoară-Farcău, Oara, Fan, Daiming, Rudler, Marika, Angrisani, Debora, García Pagán, Juan Carlos, Casanovas, Georgina, Monescillo Francia, Alberto Fernando, Lv, Yong, Hernández Gea, Virginia, Bosch, Jaime, Torres, Ferrán, Han, Guohong, Thabut, Dominique   +12 more
core   +1 more source