Results 111 to 120 of about 125,628 (234)

Evaluation of Large Language Models in the Clinical Management of Patients With Upper Gastrointestinal Bleeding: Insights From Real‐World Patient Data

DEN Open, Volume 7, Issue 1, April 2027.
Large language models are evaluated for pre‐endoscopy risk stratification and prediction of endoscopic findings in patients with upper gastrointestinal bleeding. Their performance is compared with validated clinical risk scores, conventional machine learning models, and hybrid approaches.
Mohsen Rajabnia, Farbod Davoodi, Mahsa Hajisafarali, Shadi Asadinia, Mahsa Shiri, Fatemeh Shirzad, Peyman Saeedi, Mahsa Mohammadi   +7 more
wiley   +1 more source

Randomized study comparing banding and propranolol to prevent initial variceal hemorrhage in cirrhotics with high-risk esophageal varices

, 2005
Background & Aims: Standard care for prevention of first esophageal variceal hemorrhage is β-blockade, but this may be ineffective or unsafe. Our purpose was to compare endoscopic banding with propranolol for prevention of first variceal hemorrhage ...
Savides, Thomas, Gornbein, Jeffrey, Jutabha, Rome, Jensen, Dennis M, Martin, Paul, Han, Steven-Huy   +5 more
core   +1 more source

Delayed Argon Plasma Coagulation After Endoscopic Injection Sclerotherapy for Esophageal Varices Reduces Recurrence Risk

DEN Open, Volume 7, Issue 1, April 2027.
ABSTRACT Objectives Argon plasma coagulation (APC) is commonly used as consolidation therapy after endoscopic injection sclerotherapy (EIS) for esophageal varices (EVs); however, the optimal timing of APC remains unclear. This study evaluated the association between the EIS–APC interval and clinical outcomes.
Takumi Yanagita, Takuto Hikichi, Jun Nakamura, Tsunetaka Kato, Minami Hashimoto, Mitsuru Otsuka, Eisuke Kameoka, Rei Suzuki, Mitsuru Sugimoto, Hiroyuki Asama, Hiroshi Shimizu, Kento Osawa, Rei Ohira, Keisuke Kudo, Daiki Nemoto, Masao Kobayakawa, Hiromasa Ohira   +16 more
wiley   +1 more source

Innovative Therapeutic Endoscopy of the Upper Gastrointestinal Tract: Review of the Japan Gastroenterological Endoscopy Society Core Sessions

DEN Open, Volume 7, Issue 1, April 2027.
ABSTRACT The Japanese Gastroenterological Endoscopy Society (JGES) established four core sessions on endoscopic treatment for upper gastrointestinal diseases under the theme ‘Innovative Therapeutic Endoscopy’ between 2023 and 2024. This review summarizes these sessions and compiles them as a conference report. At the 105th JGES Core Session, 14 studies
Mikitaka Iguchi, Tomoki Michida, Yasuhiko Abe, Hisashi Doyama, Noriya Uedo, Hajime Isomoto, Masayuki Ohta, Junko Fujisaki   +7 more
wiley   +1 more source

Novel Approaches to Reducing the Risk of Variceal Hemorrhage

, 2017
Complications of advanced liver disease occur at the moment of clinical significant portal hypertension. Nitric oxide (NO) dysfunction and fibrosis play an important role in the pathophysiology of PH, but other mechanisms are also involved. Non-selective
Nevens, Frederik, Frederik Nevens
core   +1 more source

Recent Development of Endo‐hepatology

DEN Open, Volume 7, Issue 1, April 2027.
ABSTRACT Endo‐hepatology is a rapidly evolving field encompassing endoscopic diagnosis and treatment of hepatobiliary diseases, primarily using endoscopic ultrasound (EUS). Since its conceptualization in 2012, the field has expanded dramatically alongside advances in interventional EUS. A landmark 2024 review broadened the concept to include endoscopic
Akira Yamamiya, Atsushi Irisawa, Yasunori Inaba, Rafael Romero‐Castro   +3 more
wiley   +1 more source

Endoscopic Injection Sclerotherapy With Pre‐deflation Ligation for Prolonged Sclerosant Retention in Esophageal Varices: A Case Report

DEN Open, Volume 7, Issue 1, April 2027.
ABSTRACT Esophageal varices are a common complication of portal hypertension, and prophylactic endoscopic injection sclerotherapy with ligation (EISL) is an established treatment option. Effective variceal thrombosis requires sufficient intravariceal retention of the sclerosant, because ethanolamine oleate exerts its thrombogenic effect through ...
Noriaki Sugawara, Taro Iwatsubo, Masatoshi Kaizuka, Sayaka Tsuji, Katsutoshi Nishian, Kazuki Takayama, Shun Sasaki, Akitoshi Hakoda, Kazuhiro Ota, Hiroki Nishikawa   +9 more
wiley   +1 more source

Management of varices and variceal hemorrhage in cirrhosis

Variceal hemorrhage is a lethal complication of cirrhosis, particularly in patients in whom clinical decompensation (i.e., ascites, encephalopathy, a previous episode of hemorrhage, or jaundice) has already developed.
Garcia Tsao, Guadalupe, Bosch i Genover, Jaume   +1 more
core  

Terlipressin for acute esophageal variceal hemorrhage

, 2003
BACKGROUND: Terlipressin (triglycyl lysine vasopressin) is a synthetic analogue of vasopressin, which has been used in the treatment of acute variceal hemorrhage.
Rockey, D. C., Ioannou, G., Doust, J.
core  

Recombinant Human Thrombopoietin Reduces the Need for Platelet Transfusion in Patients With Chronic Liver Disease and Thrombocytopenia

American Journal of Hematology, Volume 101, Issue 10, Page 2571-2580, October 2026.
ABSTRACT Chronic liver disease (CLD)‐related thrombocytopenia can limit the feasibility of invasive procedures. Recombinant human thrombopoietin (rhTPO) has demonstrated a favorable safety profile without hepatotoxicity. We evaluated the efficacy and safety of rhTPO in patients with CLD‐related thrombocytopenia who were undergoing elective invasive ...
Yifan Han, Ning Lin, Jinghang Xu, Sikui Wang, Jinglan Jin, Jia Shang, Yongning Xin, Youwen Tan, Dazhi Zhang, Jinlin Hou, Ping An, Wen Xie, Yujuan Guan, Qingfang Xiong, Hong Wu, Huiguo Ding, Yu Chen, Rongkuan Li, Zhili Wen, Mingqin Lu, Jinhui Yang, Zhongyin Zhou, Yongjian Zhou, Zujiang Yu, Kecan Lin, Wei Wang, Yan Huang, Yuemin Nan, Xinhua Luo, Rongshu Shi, Yi Kang, Tao Han, Shiyan Chen, Kai Wang, Yunfeng Shan, Jiaping Li, Pingguo Liu, Zheng Lu, Jun Chen, Zhen Liu, Liaoyun Zhang, Li Yang, Jifang Sheng, Zhan Zeng, Yanyan Yu, Xiaoyuan Xu   +45 more
wiley   +1 more source