Results 41 to 50 of about 18,807 (230)
Chemistry &Biodiversity, EarlyView.ABSTRACT The subfamily Gomphrenoideae is composed of about 480 accepted species, many of which have been historically used as medicinal plants, reason why they have been studied in terms of chemical profile, biological activity, and safety. This review consolidates the advances in research on this subfamily over the past 47 years, emphasizing its ...
Dayanna Isabel Araque Gelves +3 more
wiley +1 more source
Development of Varicella Vaccine [PDF]
The Journal of Infectious Diseases, 2008 The Oka strain of varicella-zoster virus (VZV) was first isolated from vesicles of an otherwise healthy 3-year-old boy with typical varicella. The virus was passaged 11 times in human embryonic lung fibroblasts at 34 degrees C and 12 times in guinea pig embryo fibroblasts (GPEFs) at 37 degrees C.
T Otsuka +6 more
openaire +3 more sources
Populations Addressed in Vaccines Approved via the European Medicines Agency
Clinical Pharmacology &Therapeutics, EarlyView.Therapeutic and prophylactic agents require robust evidence before patient use. Randomized controlled trials are essential for evaluating safety and efficacy but often exclude specific populations that are also targets for the intervention. This study assessed which populations are included in vaccine registration studies and/or addressed in label ...
Débora D. Gräf +3 more
wiley +1 more source
Exploring the Potential and Advancements of Circular RNA Therapeutics
Exploration, EarlyView.Given the remarkable advantages in terms of stability, sustained expression profile, safety, wide range of druggable targets, scalable and cost‐effective manufacturing capabilities, circRNA is currently undergoing intensive investigation for various therapeutic applications such as vaccines, protein replacement, genetic disease treatment, gene therapy,
Lei Wang +6 more
wiley +1 more source
Varicella epidemiology in Latin America and the Caribbean
Expert Review of Vaccines, 2018 Introduction: The Latin American Society of Pediatric Infectious Diseases (SLIPE), with the support of the Americas Health Foundation (AHF), has developed a position paper on varicella prevention in Latin America and Caribbean countries (LAC).
Maria L. Ávila-Agüero +13 more
doaj +1 more source
Current Progress in Targeting Human Cytomegalovirus Infection
iLABMED, EarlyView.This review highlights recent advances in the mechanisms by which human cytomegalovirus (HCMV) maintains its genome in infected cells, as well as the cellular factors and viral antigens that modulate viral reactivation, which reveal potential targets for addressing HCMV infection.
Yonggang Pei, Jun Chen
wiley +1 more source
Pediatric Hematology Oncology Journal, 2019 Background: Varicella infection in children with Acute Lymphoblastic Leukemia (ALL) is associated with significant morbidity and mortality. Immunisation against varicella infection is not mandatory as per the national immunisation program in India and ...
Vijay Guru +2 more
doaj
Severe varicella in persons vaccinated with varicella vaccine (breakthrough varicella): a systematic literature review [PDF]
Expert Review of Vaccines, 2017 Varicella vaccines are highly effective at preventing disease, but varicella may occur among vaccinated persons (termed breakthrough varicella). Breakthrough varicella is generally mild, but severe cases have been reported. The objective of this review is to describe severe breakthrough varicella.
Mona Marin +2 more
openaire +3 more sources
Journal of General and Family Medicine, EarlyView.This case report describes a 24‐year‐old woman with trisomy 21 and an incomplete childhood vaccination history who developed severe disseminated varicella and varicella pneumonia. Chest CT on admission day 3 revealed scattered small nodules in both lung fields, characteristic of varicella pneumonia.
Satoshi Inaba +3 more
wiley +1 more source
Burden of varicella in the Asia-Pacific region: a systematic literature review
Expert Review of Vaccines, 2019 Introduction: Varicella is a highly contagious infection that can lead to serious complications, particularly in high-risk groups; however, it is vaccine preventable.
Anne Eng Neo Goh +8 more
doaj +1 more source