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Mechanism of Varices and Variceal Bleeding in Cirrhosis
2020Variceal formation and bleeding from varices are the endpoint of a series of pathophysiological events that occur in patients with cirrhosis who develop clinically significant portal hypertension. Through decades of animal model and human studies, the pathomechanisms that lead to the formation of varices and bleeding have been delineated with ...
Varghese Thomas +3 more
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Current Treatment Options in Gastroenterology, 2002
Primary prophylaxis: Patients with cirrhosis who have esophageal varices but who have never had a bleeding episode may be treated medically or endoscopically. Without treatment, approximately 30% of cirrhotic patients with varices bleed and this risk is reduced by approximately 50% with therapy.
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Primary prophylaxis: Patients with cirrhosis who have esophageal varices but who have never had a bleeding episode may be treated medically or endoscopically. Without treatment, approximately 30% of cirrhotic patients with varices bleed and this risk is reduced by approximately 50% with therapy.
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Digestive Diseases, 1998
Esophageal varices are the most common site of variceal bleeding. However, bleeding from varices that are not located in the esophagus may account for up to 30% of all variceal bleeding. Significant varices can occur in the stomach, duodenum, jejunum, ileum, colon, rectum, and biliary tree. They can also occur at the site of a surgical ostomy.
R, Kotfila, W, Trudeau
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Esophageal varices are the most common site of variceal bleeding. However, bleeding from varices that are not located in the esophagus may account for up to 30% of all variceal bleeding. Significant varices can occur in the stomach, duodenum, jejunum, ileum, colon, rectum, and biliary tree. They can also occur at the site of a surgical ostomy.
R, Kotfila, W, Trudeau
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Endoscopic Management of Varices and Variceal Hemorrhage
2010Acute variceal hemorrhage is a medical emergency. Approximately 40% of patients with cirrhosis are found to have esophageal varices on endoscopic evaluation (Bosch et al.2003), and approximately one third of patients will experience variceal hemorrhage (Kleber et al.
Joshua D. Hall, Subbaramiah Sridhar
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Gastroenterology Clinics of North America, 1988
Figure 2 is the algorithm followed in our institution for management of acute variceal hemorrhage. A small percentage of patients who present with active variceal hemorrhage will stop bleeding after gastric lavage alone. However, most patients require an intravenous vasopressin infusion at a dose of 0.4 units per minute, preferably combined with ...
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Figure 2 is the algorithm followed in our institution for management of acute variceal hemorrhage. A small percentage of patients who present with active variceal hemorrhage will stop bleeding after gastric lavage alone. However, most patients require an intravenous vasopressin infusion at a dose of 0.4 units per minute, preferably combined with ...
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Gastrointestinal Endoscopy Clinics of North America, 1994
Numerous conditions lead to portal hypertension with the development of esophageal varices. Treatment for acute variceal hemorrhage should progress in a logical, stepwise fashion. Therapy after fluid resuscitation includes vasopressin, somatostatin, or a Sengstaken-Blakemore tube.
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Numerous conditions lead to portal hypertension with the development of esophageal varices. Treatment for acute variceal hemorrhage should progress in a logical, stepwise fashion. Therapy after fluid resuscitation includes vasopressin, somatostatin, or a Sengstaken-Blakemore tube.
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The American Journal of Surgery, 1990
Bleeding from esophageal varices is related to the size and pressure of varices, endoscopic danger signs, and severity of liver failure. Prevention of bleeding with propranolol has given conflicting results in controlled trials, but is a safe treatment.
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Bleeding from esophageal varices is related to the size and pressure of varices, endoscopic danger signs, and severity of liver failure. Prevention of bleeding with propranolol has given conflicting results in controlled trials, but is a safe treatment.
openaire +2 more sources