Results 81 to 90 of about 41,899 (242)

Acute Upper Gastrointestinal Bleeding in a Tertiary Care Centre of Nepal

open access: yesJournal of Nepal Medical Association, 2017
Introduction: AUGIB is characterized by hematemesis or melena or both. Peptic ulcers and variceal bleed account for majority of cases. Use of proton pump inhibitors in current era is associated with a gradual reduction in burden of peptic ulcer disease ...
Mukesh Sharma Paudel   +6 more
doaj   +1 more source

A Multicenter Retrospective Study of HbH in China Including 1421 Patients Over a 12‐Year Timespan

open access: yeseJHaem, Volume 6, Issue 4, August 2025.
ABSTRACT Background Hemoglobin H (HbH) disease is a relatively common genetic disorder worldwide. However, the lack of long‐term follow‐up studies involving large patient cohorts has limited our understanding of its clinical features, disease progression, and outcomes.
Hangning Shang   +14 more
wiley   +1 more source

Analysis of Late Complications Associated With Hematopoietic Stem Cell Transplantation in Patients With Dyskeratosis Congenita

open access: yesPediatric Blood &Cancer, Volume 72, Issue 8, August 2025.
ABSTRACT Background Dyskeratosis congenita (DKC) is a genetic disorder frequently complicated by bone marrow failure (BMF). Hematopoietic stem cell transplantation (HSCT) remains the only curative treatment option for BMF in DKC. However, late complications of DKC, especially pulmonary fibrosis (PF), pose significant challenges.
Takashi Koike   +12 more
wiley   +1 more source

Diabetes Mellitus in Patients With Autoimmune Hepatitis: Frequency, Risk Factors and Effect on Outcome

open access: yesAlimentary Pharmacology &Therapeutics, Volume 62, Issue 3, Page 319-329, August 2025.
New‐onset DM occurred in 13% of patients with AIH, was related to older age, non‐Caucasian ethnicity, higher prednisolone dose, higher BMI at diagnosis and weight gain and was an independent predictor of all‐cause death/transplantation and of cirrhosis development, underlining the need to minimise steroid burden in AIH.
Sarah Flatley   +6 more
wiley   +1 more source

Oesophageal varices predict complications in compensated advanced non-alcoholic fatty liver disease

open access: yesJHEP Reports, 2023
Background & Aims: We aimed to evaluate the impact of oesophageal varices (OV) and their evolution on the risk of complications of compensated advanced chronic liver disease (cACLD) caused by non-alcoholic fatty liver disease (NAFLD).
Grazia Pennisi   +28 more
doaj  

Meta‐Analysis: Effects of Steatotic Liver Disease‐Associated Genetic Risk Alleles on Longitudinal Outcomes

open access: yesAlimentary Pharmacology &Therapeutics, Volume 62, Issue 3, Page 244-276, August 2025.
Genetic variants associated with risk of steatotic liver disease (SLD) may also influence clinical events. A systematic review and meta‐analysis consisting of 288,423 patients across 40 studies found that variants in PNPLA3, TM6SF2 and MBOAT7 are significantly associated with hepatic outcomes, with modest effects on extrahepatic outcomes.
Matthew Kubina   +15 more
wiley   +1 more source

The impact of immature granulocytes on the outcome of patients with decompensated cirrhosis

open access: yesEuropean Journal of Clinical Investigation, Volume 55, Issue 8, August 2025.
Immature granulocyte (IG) count and percentage had a predictive role in patients with decompensated cirrhosis, making them an objective and easily available marker of prognosis for this group of patients. In addition, IG percentage was the only factor independently associated with transplant‐free survival.
Magdalini Adamantou   +10 more
wiley   +1 more source

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