Results 71 to 80 of about 5,659 (257)
Molecular Oncology, EarlyView.LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang +9 more
wiley +1 more source
Cases of apparent enclisis on past participles in Romance varieties
Isogloss, 2015 This paper deals with cases of apparent enclisis on past participles in North-Western Italian varieties. It is claimed that these cases do not involve clitic pronouns, but weak pronouns in the sense of Cardinaletti and Starke (1999).
Anna Cardinaletti
doaj +3 more sources
Varieties and Covarieties of Languages (Extended Abstract)
Electronic Notes in Theoretical Computer Science, 2013 AbstractBecause of the isomorphism (X×A)→X≅X→(A→X), the transition structure of a deterministic automaton with state set X and with inputs from an alphabet A can be viewed both as an algebra and as a coalgebra. This algebra-coalgebra duality goes back to Arbib and Manes, who formulated it as a duality between reachability and observability, and is ...
Jan Rutten +2 more
openaire +2 more sources
Spatial biology in cancer epigenetics
Molecular Oncology, EarlyView.Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley +1 more source
ADP‐ribosylation: An emerging regulator of the epigenome
Molecular Oncology, EarlyView.ADP‐ribosylation has emerged as a dynamic epigenetic signaling mechanism that modifies histones and chromatin‐associated proteins. Through coordinated PARylation and MARylation, it integrates with other histone modifications to regulate chromatin structure, transcription factor activity, and gene expression, influencing genome function and disease ...
Cristel V. Camacho +2 more
wiley +1 more source
A Neural Approach to Language Variety Translation
CoRR, 2018 In this paper we present the first neural-based machine translation system trained to translate between standard national varieties of the same language. We take the pair Brazilian - European Portuguese as an example and compare the performance of this method to a phrase-based statistical machine translation system.
Ruiz Costa-Jussà, Marta +2 more
openaire +4 more sources
FEBS Open Bio, EarlyView.Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley +1 more source
FEBS Open Bio, EarlyView.UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová +2 more
wiley +1 more source
L'émergence des parlers créoles et l'évolution des langues romanes
Études Créoles, 2016 In this article, I revisit two apparently conflicting positions about similarities between the emergence of French creoles and that of the Romance languages.
Salikoko S. Mufwene
doaj +1 more source
Directed evolution of enzymes at the crossroads of tradition and innovation
FEBS Open Bio, EarlyView.An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova +2 more
wiley +1 more source