Results 131 to 140 of about 9,215,739 (339)

Cyclic nucleotide signaling as a drug target in retinitis pigmentosa

FEBS Letters, EarlyView.
Disruptions in cGMP and cAMP signaling can contribute to retinal dysfunction and photoreceptor loss in retinitis pigmentosa. This perspective examines the mechanisms and evaluates emerging evidence on targeting these pathways as a potential therapeutic strategy to slow or prevent retinal degeneration.
Katri Vainionpää, Ahmed B. Montaser, Henri Leinonen   +2 more
wiley   +1 more source

Cumulant varieties

Journal of Symbolic Computation, 2006
AbstractFor a discrete distribution in Rd on a finite support D probabilities and moments are algebraically related. If there are n=|D| support points then there are n probabilities p(x),x∈D and n basic moments. By suitable interpolation of the probabilities using a Gröbner basis method, high order moments can be express linearly in terms of n basic ...
PISTONE, Giovanni, WYNN H.
openaire   +3 more sources

The current matters of adaptation of the Ukrainian Laws to the EU legislation in the sphere of plant variety right enforcement

Plant Varieties Studying and Protection, 2006
The analysis of the Law of Ukraine "On the protection of plant variety rights" in relation to the provisions of plant variety right enforcement as for their correspondence to the Council Regulation N 2100 ...
О. В. Жмурко, Є. В. Тисячний, Н. Б. Якубенко   +2 more
doaj   +1 more source

MET variants with activating N‐lobe mutations identified in hereditary papillary renal cell carcinomas still require ligand stimulation

Molecular Oncology, EarlyView.
MET variants in the N‐lobe of the kinase domain, found in hereditary papillary renal cell carcinoma, require ligand stimulation to promote cell transformation, in contrast to other RTK variants. This suggests that HGF expression in the microenvironment is important for tumor growth in such patients. Their sensitivity to MET inhibitors opens the way for
Célia Guérin, Audrey Vinchent, Marie Fernandes, Isabelle Damour, Agathe Laratte, Rémi Tellier, Gabriella O. Estevam, Jean‐Pascal Meneboo, Céline Villenet, Clotilde Descarpentries, James S. Fraser, Martin Figeac, Alexis B. Cortot, Etienne Rouleau, David Tulasne   +14 more
wiley   +1 more source

Updating methodological and source database of binominal denominations of introduced cultivars with elements of extrapolation

Plant Varieties Studying and Protection, 2013
The article discloses the meaning of botanical semantics, highlights practical appliance of binary scientific botanic nomenclature during plant varieties identification.
Н. В. Лещук, Н. П. Костенко, Н. В. Павлюк, В. А. Павлюк   +3 more
doaj   +1 more source

Cone-in-cone: how it occurs in the Devonian; Series in Pennsylvania (U.S.A.); with Further Details of its Structure, Varieties, etc. [PDF]

, 1894
W. S. Gresley
openalex   +1 more source

Peripheral blood proteome biomarkers distinguish immunosuppressive features of cancer progression

Molecular Oncology, EarlyView.
Immune status significantly influences cancer progression. This study used plasma proteomics to analyze benign 67NR and malignant 4T1 breast tumor models at early and late tumor stages. Immune‐related proteins–osteopontin (Spp1), lactotransferrin (Ltf), calreticulin (Calr) and peroxiredoxin 2 (Prdx2)–were associated with systemic myeloid‐derived ...
Yeon Ji Park, Jae Won Oh, Hyewon Chung, Jung Won Kwon, Yi Rang Na, Kwang Pyo Kim, Seung Hyeok Seok   +6 more
wiley   +1 more source

Sowing and bread-making quality indexes of seeds of common winter wheat varieties damaged by the sunn pest (Eurygaster integriceps Put.)

Plant Varieties Studying and Protection, 2007
Consideration is being given for seeds of different common winter wheat varieties damaged by the sunn pest. The level of such damage influence on sowing and bread-making quality indexes is investigated.
Г. А. Заякіна, О. О. Шовгун, О. О. Бадяка   +2 more
doaj   +1 more source

Flax Variety Trial [PDF]

, 2015
Flax (Linum usitatissimum L.) is a multi-purpose crop grown for its fiber, oil (linseed oil), and meal. The importance of flax as a major crop in the United States dropped drastically in the 1980’s when latex paints replaced linseed oil based paint ...
Calderwood, Lily, Cummings, Erica, Darby, Heather, Gupta, Abha, Post, Julian, Ziegler, Sara   +5 more
core   +1 more source

Adverse prognosis gene expression patterns in metastatic castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
We aggregated a cohort of 1012 mCRPC tissue samples from 769 patients and investigated the association of gene expression‐based pathways with clinical outcomes. Loss of AR signaling, high proliferation, and a glycolytic phenotype were independently prognostic for poor outcomes, and an adverse transcriptional feature score incorporating these pathways ...
Marina N. Sharifi, Eric Feng, Nicholas R. Rydzewski, Amy K. Taylor, Jamie M. Sperger, Yue Shi, Kyle T. Helzer, Matthew L. Bootsma, Viridiana Carreno, Alex H. Chang, Luke A. Nunamaker, Grace C. Blitzer, Tianfu Andy Shang, Aishwarya Subramanian, Anders Bjartell, Andreas Josefsson, Pernilla Wikström, Emily Feng, Manish Kohli, Rendong Yang, Scott M. Dehm, Eric J. Small, Rahul Aggarwal, David A. Quigley, Joshua M. Lang, Shuang G. Zhao, Martin Sjöström   +26 more
wiley   +1 more source