Development of disease-resistant, stable high-yielding, and high-quality rice variety "Yunjing-60" through double-cropping acceleration and intensive multi-environment selection in mid-altitude regions. [PDF]
BMC Plant BiolKou S +8 more
europepmc +1 more source
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
Requisite variety and intercultural teams: to what extent is Ashby's law useful ? [PDF]
Requisite variety and intercultural teams: To what extent is Ashby's law useful? The “Law of Requisite Variety” (LRV) is frequently evoked to explain the design, functioning and performance of intercultural teams.
A. Bartel-Radic, N. Lesca
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Ruminal and Postruminal Digestibility Parameters of Locally Produced Non-GMO Full-Fat Soybeans, Extruded Full-Fat Soybeans and Soybean Cake in Cattle. [PDF]
Animals (Basel)Śliwiński B, Witaszek K, Kostecki J.
europepmc +1 more source
Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization
Molecular Oncology, EarlyView.In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu +13 more
wiley +1 more source
Impact of State of Ripeness and Culinary Treatments on the Hypoglycemic, Antioxidant, and Nutritional Properties of Two Varieties of <i>Solanum aethiopicum</i> L. Fruit. [PDF]
Int J Food SciMaffo Tazoho G +7 more
europepmc +1 more source
Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma
Molecular Oncology, EarlyView.Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski +10 more
wiley +1 more source
Experimental evolution reveals genomic signatures of variety-specific selection of Cercospora beticola in Germany. [PDF]
Sci RepYang Y +9 more
europepmc +1 more source
Liquid biopsy‐based diagnostic evaluation of hypermethylated CpG sites for ovarian cancer diagnosis
Molecular Oncology, EarlyView.This schematic outlines the workflow from biomarker identification to duplex MethyLight assay validation for epithelial ovarian cancer diagnosis using cfDNA‐based liquid biopsy. Initial screening of hypermethylated CpG candidates (cg02957270, cg10061138 cg00480298, COL2A1) was performed in tissue using ARMS‐PCR, COBRA, qPCR and image analysis. Selected
Deepa Bisht +3 more
wiley +1 more source
Key Metrics System for Variety Steering in Mass Customization
The main goal of this paper is to provide a key metrics system for variety steering in mass customization. We distinguish between objective and subjective customer needs.
Friedrich, Gerhard +3 more
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