Results 141 to 150 of about 869,747 (334)

Reasoned opinion on the modification of the existing MRLs for fluopyram in various crops

EFSA Journal, 2014
In accordance with Article 6 of Regulation (EC) No 396/2005, Germany, hereafter referred to as the evaluating Member State (EMS), received an application from Bayer CropScience AG to modify the existing MRLs for the active substance fluopyram in various ...
European Food Safety Authority
doaj   +1 more source

Modeling the growth dynamics of four candidate crops for Controlled Ecological Life Support Systems (CELSS) [PDF]

The production of food for human life support for advanced space missions will require the management of many different crops. The research to design these food production capabilities along with the waste management to recycle human metabolic wastes and
Volk, Tyler
core   +1 more source

LINC01116, a hypoxia‐lncRNA marker of pathological lymphangiogenesis and poor prognosis in lung adenocarcinoma

Molecular Oncology, EarlyView.
The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola, Rafael Lopes Goncalves, Marin Truchi, Caroline Lacoux, Célia Scribe, Hugo Cadis, Laetitia Guardini, Sophie Bekisz, Marius Ilié, Paul Hofman, Georges Vassaux, Bernard Mari, Roger Rezzonico   +12 more
wiley   +1 more source

Grain-supply response in Ethiopia: An error-correction approach [PDF]

This paper quantifies the responsiveness of producers of teff, wheat, maize and sorghum to incentives using an error-correction model (ECM). It is found that planned supply of these crops is positively affected by own price, negatively by prices of ...
Alemu, Zerihun Gudeta, Oosterhuizen, K., van Schalkwyk, Herman D.   +2 more
core   +1 more source

Improvement of three nucleic acid isolation protocols for an overall diagnosis of viruses on six vegetative propagated plants [PDF]

, 2013
Biological Resources Center (BRCs) must be able to guarantee the sanitary status of the resources they distribute, in order to prevent the spread or emergence of diseases.
Bernardo, Pauline, Da Silva Mendoça, D.M., Fernandez, Emmanuel, Filloux, Denis, Galzi, Serge, Grisoni, Michel, Julian, Charlotte, Pavis, Claudie, Roumagnac, Philippe   +8 more
core  

ATF4‐mediated stress response as a therapeutic vulnerability in chordoma

Molecular Oncology, EarlyView.
We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone, James Dunford, Eleanor Calcutt, Vicki Gamble, Filiz Senbabaoglu Aksu, Lorena Ligammari, Georgina Wherry, Giorgia Gaeta, John C. Christianson, Adrienne M. Flanagan, Udo Oppermann, Adam P. Cribbs   +11 more
wiley   +1 more source

SOME PLANT GROWTH PROMOTING TRAITS OF STREPTOMYCES SPECIES ISOLATED FROM VARIOUS CROP RHIZOSPHERES WITH HIGH ROOT COLONIZATION ABILITY OF SPINACH (SPINACIA OLERACEA L.)

, 2021
M. SARAYLOU, Habiballah Nadian Ghomsheh, Naeimeh Enayatizamir, N. RANGZAN, Savanah Senn   +4 more
openalex   +1 more source

Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma

Molecular Oncology, EarlyView.
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken, Andrea Abel Gutierrez, Imke van Rossum, Cornelia G. Spruijt, Michiel Vermeulen, Guido van Mierlo, Blanca Scheijen, Annemiek B. van Spriel   +7 more
wiley   +1 more source

Modification of the existing maximum residue levels for acetamiprid in various crops. [PDF]

EFSA J, 2021
EFSA (European Food Safety Authority), Bellisai G, Bernasconi G, Brancato A, Carrasco Cabrera L, Ferreira L, Giner G, Greco L, Jarrah S, Kazocina A, Leuschner R, Magrans JO, Miron I, Nave S, Pedersen R, Reich H, Ruocco S, Santos M, Scarlato AP, Theobald A, Vagenende B, Verani A.   +21 more
europepmc   +1 more source

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon, Peter T. Gallagher, Orly I. Richter, Neermala Poudel Neupane, Amy C. Mandigo, Jennifer J. McCann, Emanuela Dylgjeri, Irina Vasilevskaya, Christopher McNair, Channing J. Paller, Wm. Kevin Kelly, Karen E. Knudsen, Matthew J. Schiewer, Ayesha A. Shafi   +13 more
wiley   +1 more source