Results 41 to 50 of about 14,212,615 (258)

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

FEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi, Pilar Samperio Ventayol, Natalie Burkard, Nicolas Schlegel, Carmen Aguilar, Sina Bartfeld   +5 more
wiley   +1 more source

Teaching medical students ultrasound-guided vascular access - which learning method is best?

, 2017
Introduction Ultrasound is recommended to guide insertion of peripheral intravenous vascular cannulae (PIVC) where difficulty is experienced. Ultrasound machines are now common-place and junior doctors are often expected to be able to use them.
Alwin Lian, James C.R. Rippey, Lian, Alwin, Peter J. Carr, Carr, Peter J, Rippey, James CR   +5 more
core   +1 more source

What are the observed procedural costs of vascular access surgery? Protocol for a systematic review

BMJ Open
Introduction A central component in the introduction of a novel surgical procedure or technique is an evaluation of its cost efficiency when compared with a benchmark standard of care.
Karen Stevenson, Andrew Jackson, Catrin Jones, Peter Thomson, Ram Kasthuri, David Kingsmore, Lucian Gaianu, Emma Aitken, Ben Edgar, Callum Stove   +9 more
doaj   +1 more source

Implementation and evaluation of short peripheral intravenous catheter flushing guidelines: a stepped wedge cluster randomised trial

BMC Medicine, 2020
Background Peripheral intravenous catheters (PIVCs) are ubiquitous medical devices, crucial to providing essential fluids and drugs. However, post-insertion PIVC failure occurs frequently, likely due to inconsistent maintenance practice such as flushing.
Samantha Keogh, Caroline Shelverton, Julie Flynn, Gabor Mihala, Saira Mathew, Karen M. Davies, Nicole Marsh, Claire M. Rickard   +7 more
doaj   +1 more source

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Surveillance of vascular access and prevention of catheter-related infections: the key role of the critical care nurse

, 2023
openABSTRACT BACKGROUND: La gestione degli accessi vascolari è una fase critica nella pratica clinica, spesso associata a un elevato rischio di infezioni.
PAROLIN, GIULIANA
core  

VASCULAR ACCESS

Revista Médica Clínica Las Condes, 2017
: Vascular access, arterial and venous, at peripheral and more central sites is a core skill, yet is not always well taught or in core training. Like many procedures, it can be simple to learn the basics, but hazards await inexperienced operators ...
Andrew Bodenham, Dr.
doaj   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source

Detailed ultrasonographic assessment of calcified arteries before arterio-venous fistula construction and fistula outcomes - a prospective observational study

BMC Nephrology
Background Arterial calcifications (mainly mediocalcinosis) are highly prevalent in patients on hemodialysis. Severe calcifications reduce the possibility of a forearm arterio-venous fistula (AVF) construction, reduce maturation rates and increase the ...
Jakob Gubensek, Denis Fornazaric, Matej Zrimsek   +2 more
doaj   +1 more source

Decoding the dynamic extracellular matrix in cancer—3D models and bioscaffolds rewire the rules of tumor progression

FEBS Letters, EarlyView.
Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani, Konstantinos Spanopoulos, Zoi Piperigkou, Nikos K. Karamanos   +3 more
wiley   +1 more source