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Vascular Adhesion Protein-1 Determines the Cellular Properties of Endometrial Pericytes [PDF]

open access: yesFrontiers in Cell and Developmental Biology, 2021
Vascular adhesion protein-1 (VAP-1) is an inflammation-inducible adhesion molecule and a primary amine oxidase involved in immune cell trafficking. Leukocyte extravasation into tissues is mediated by adhesion molecules expressed on endothelial cells and ...
Seley Gharanei   +19 more
doaj   +9 more sources

Vascular-adhesion protein 1 in giant cell arteritis and polymyalgia rheumatica [PDF]

open access: goldFrontiers in Medicine
Vascular adhesion protein-1 (VAP-1) is a type 2 transmembrane sialoglycoprotein with oxidative deamination functionality, encoded by the amine oxidase copper-containing 3 (AOC3) gene.
Simon M. Petzinna   +2 more
doaj   +6 more sources

Vascular Adhesion Protein 1 in the Eye [PDF]

open access: yesJournal of Ophthalmology, 2013
Semicarbazide-sensitive amine oxidase/vascular adhesion protein-1 (SSAO/VAP-1), a dual-function molecule with adhesive and enzymatic properties, is expressed on the surface of vascular endothelial cells of mammals.
Wenting Luo   +3 more
doaj   +6 more sources

The role of vascular adhesion protein‐1 in diabetes and diabetic complications [PDF]

open access: yesJournal of Diabetes Investigation
Vascular adhesion protein‐1 (VAP‐1) plays a dual role with its adhesive and enzymatic properties, facilitating leukocyte migration to sites of inflammation and catalyzing the breakdown of primary amines into harmful by‐products, which are linked to ...
I‐Weng Yen, Hung‐Yuan Li
doaj   +4 more sources

Functional modulation of vascular adhesion protein-1 by a novel splice variant. [PDF]

open access: yesPLoS ONE, 2013
Vascular Adhesion Protein-1 (VAP-1) is an endothelial adhesion molecule belonging to the primary amine oxidases. Upon inflammation it takes part in the leukocyte extravasation cascade facilitating transmigration of leukocytes into the inflamed tissue ...
Sam Kaitaniemi   +5 more
doaj   +5 more sources

Vascular Adhesion Protein 1 Mediates Gut Microbial Flagellin-Induced Inflammation, Leukocyte Infiltration, and Hepatic Steatosis [PDF]

open access: goldSci, 2021
Toll-like receptor 5 ligand, flagellin, and vascular adhesion protein 1 (VAP-1) are involved in non-alcoholic fatty liver disease. This study aimed to determine whether VAP-1 mediates flagellin-induced hepatic fat accumulation.
Raine Toivonen   +9 more
doaj   +2 more sources

Soluble Vascular Adhesion Protein 1 (sVAP-1) as a biomarker for pregnancy complications: A pilot study. [PDF]

open access: yesPLoS ONE, 2023
BackgroundVascular adhesion protein 1 (VAP-1) has been implicated in a wide range of clinical conditions. Moreover, serum levels are associated with disease prediction and progression in several clinical studies.
Marianna Danielli   +5 more
doaj   +2 more sources

Vascular Adhesion Protein-1 (VAP-1)/Semicarbazide-Sensitive Amine Oxidase (SSAO): A Potential Therapeutic Target for Atherosclerotic Cardiovascular Diseases [PDF]

open access: yesFrontiers in Pharmacology, 2021
Vascular adhesion protein-1 (VAP-1) is a semicarbazide-sensitive amine oxidase (SSAO), whose enzymatic activity regulates the adhesion/exudation of leukocytes in/from blood vessels.
Hui Li   +5 more
doaj   +2 more sources

Comparison of Inhibitor and Substrate Selectivity between Rodent and Human Vascular Adhesion Protein-1 [PDF]

open access: yesMediators of Inflammation, 2020
Vascular adhesion protein-1 (VAP-1) is an ectoenzyme that functions as a copper-containing amine oxidase and is involved in leukocyte adhesion at sites of inflammation.
Ryo Kubota   +6 more
doaj   +2 more sources

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