Results 291 to 300 of about 444,049 (319)

Hepatic consequences of vascular adhesion protein-1 expression

Journal of Neural Transmission, 2011
The liver is constantly exposed to antigens present in the blood and to particulate antigens delivered from the gut. To maintain effective levels of immune surveillance and yet tolerate food antigens, the hepatic environment has become highly specialised.
Chris J, Weston, David H, Adams
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Vascular adhesion protein‐1 in human ischaemic stroke

Neuropathology and Applied Neurobiology, 2008
Aims: Leukocyte extravasation exacerbates tissue injury after ischaemic stroke. Vascular adhesion protein‐1 (VAP‐1) is an endothelial adhesion molecule with the potential capacity to guide transmigration of inflammatory cells into ischaemic brain. Moreover, VAP‐1 could worsen ischaemic brain injury due to its function as a semicarbazide‐sensitive ...
L, Airas, P J, Lindsberg, M-L, Karjalainen-Lindsberg, I, Mononen, K, Kotisaari, D J, Smith, S, Jalkanen   +6 more
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Vascular adhesion protein‐1 (VAP‐1) is overexpressed in psoriatic patients

Journal of the European Academy of Dermatology and Venereology, 2006
AbstractBackground  Vascular adhesion protein (VAP)‐1 is an adhesion molecule with an enzymatic activity that partakes in the migration process of lymphocytes.Objectives  The aim of this study was to investigate the expression of VAP‐1 in the skin and serum of psoriatic patients.Material and methods  Seventy‐one patients suffering from psoriasis aged ...
A, Madej, A, Reich, A, Orda, J C, Szepietowski   +3 more
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Vascular adhesion protein-1 (VAP-1)

2007
In 1980s the leukocyte adhesion molecules and their ligands on the vascular endothelium were thought to explain tissue-selective, or even tissue-specific, leukocyte traffic. At the same time it became apparent that vessels in inflamed joints displayed binding characteristics clearly distinct from those in peripheral lymph nodes, gut and skin. In search
Marko Salmi, Sirpa Jalkanen
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Developmental regulation of the adhesive and enzymatic activity of vascular adhesion protein-1 (VAP-1) in humans

Blood, 2006
Vascular adhesion protein-1 (VAP-1) is a homodimeric glycoprotein that belongs to a unique subgroup of cell-surface-expressed oxidases. In adults, endothelial VAP-1 supports leukocyte rolling, firm adhesion, and transmigration in both enzyme activity-dependent and enzyme activity-independent manner.
Marko, Salmi, Sirpa, Jalkanen
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A mouse molecular mimic of human vascular adhesion protein-1

Molecular Immunology, 1997
Human vascular adhesion protein-1 (VAP-1) is an endothelial sialoglycoprotein which exists in forms of Mr 90000 and 170000 and mediates lymphocyte binding to vessels under shear. VAP-1 is functionally defined by an inhibitory mouse mAb 1B2. A large-scale immunoaffinity purification of VAP-1 from human tonsil lysates was performed to determine the ...
M, Salmi, D J, Smith, P, Bono, T, Leu, J, Hellman, M T, Matikainen, S, Jalkanen   +6 more
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Circulating renalase, catecholamines, and vascular adhesion protein 1 in hypertensive patients

Journal of the American Society of Hypertension, 2015
The aim of the study was to estimate and correlate circulating levels of renalase, vascular adhesion protein-1 (VAP-1), catecholamines in patients with primary hypertension. The renalase, VAP-1, and catecholamines concentration was estimated in 121 hypertensive patients.
Dominika, Maciorkowska, Edyta, Zbroch, Jolanta, Malyszko   +2 more
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Overexpression of vascular adhesion protein‐1 is associated with poor prognosis of astrocytomas

Apmis, 2016
Vascular adhesion protein‐1 (VAP‐1) is one of the endothelial adhesion molecules that is believed to play a role in tumor progression and metastasis, supporting cancer cell extravasation. Very few studies have been performed on analyzing the contribution of VAP‐1 in brain tumor.
Shu-Jyuan Chang, Chun-Chieh Wu, Chee-Yin Chai   +2 more
exaly   +3 more sources

Organ‐selective regulation of vascular adhesion protein‐1 expression in man

European Journal of Immunology, 1997
AbstractVascular adhesion protein‐1 (VAP‐1) is an endothelial molecule which mediates lymphocyte binding to endothelium in peripheral lymph nodes and at certain sites of inflammation. The expression of VAP‐1 in vivo is strongly up‐regulated in inflamed tissues, such as gut and skin.
A M, Arvilommi, M, Salmi, S, Jalkanen
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Inhibition of vascular adhesion protein‐1 suppresses endotoxin‐induced uveitis

The FASEB Journal, 2007
Inflammatory leukocyte accumulation is a common feature of major ocular diseases, such as uveitis, diabetic retinopathy, and age‐related macular degeneration. Vascular adhesion protein‐1 (VAP‐1), a cell surface and soluble molecule that possesses semi‐carbazide‐sensitive amine oxidase (SSAO) activity, is involved in leukocyte ...
Kousuke, Noda, Shinsuke, Miyahara, Toru, Nakazawa, Lama, Almulki, Shintaro, Nakao, Toshio, Hisatomi, Haicheng, She, Kennard L, Thomas, Rebecca C, Garland, Joan W, Miller, Evangelos S, Gragoudas, Yosuke, Kawai, Yukihiko, Mashima, Ali, Hafezi-Moghadam   +13 more
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