Results 51 to 60 of about 867,365 (301)

Pharmacological induction of leukotriene B4 12-hydroxydehydrogenase (LTB4DH) in human neutrophils and its potential in the treatment of myocardial injury [PDF]

open access: yes, 2011
Oral Presentation: Session S29 - Vascular Biology, Basic Research: abstract no. 263postprint16th World Congress on Heart Disease, International Academy of Cardiology, Annual Scientific Sessions, Vancouver, BC, Canada, 23-26 July 2011, Oral Presentation:
Han, Y, Le, XC, Rong, J, Wei, L, Xia, Z
core  

Manual measurement of retinal bifurcation features [PDF]

open access: yes, 2010
This paper introduces a new computerized tool for accurate manual measurement of features of retinal bifurcation geometry, designed for use in investigating correlations between measurement features and clinical conditions.
Al-Diri, Bashir   +3 more
core   +1 more source

Vascular biology of metabolic syndrome [PDF]

open access: yesJournal of Vascular Surgery, 2011
The metabolic syndrome is a constellation of clinical risk factors comprising atherogenic dyslipidemia (low high-density lipoprotein and high triglycerides levels), elevated blood pressure, elevated plasma glucose, a prothrombotic state, and a proinflammatory state accompanied by an increased risk for cardiovascular disease and type 2 diabetes mellitus.
Vykoukal, Daynene, Davies, Mark G.
openaire   +2 more sources

Hematopoietic (stem) cells—The elixir of life?

open access: yesFEBS Letters, EarlyView.
The aging of HSCs (hematopoietic stem cells) and the blood system leads to the decline of other organs. Rejuvenating aged HSCs improves the function of the blood system, slowing the aging of the heart, kidney, brain, and liver, and the occurrence of age‐related diseases.
Emilie L. Cerezo   +4 more
wiley   +1 more source

ROS-producing immature neutrophils in giant cell arteritis are linked to vascular pathologies

open access: yesJCI Insight, 2020
Giant cell arteritis (GCA) is a common form of primary systemic vasculitis in adults, with no reliable indicators of prognosis or treatment responses.
Lihui Wang   +12 more
doaj   +1 more source

Function‐driven design of a surrogate interleukin‐2 receptor ligand

open access: yesFEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang   +9 more
wiley   +1 more source

Mechanisms of parasite‐mediated disruption of brain vessels

open access: yesFEBS Letters, EarlyView.
Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira   +3 more
wiley   +1 more source

YAP1::TFE3 mediates endothelial‐to‐mesenchymal plasticity in epithelioid hemangioendothelioma

open access: yesMolecular Oncology, EarlyView.
The YAP1::TFE3 fusion protein drives endothelial‐to‐mesenchymal transition (EndMT) plasticity, resulting in the loss of endothelial characteristics and gain of mesenchymal‐like properties, including resistance to anoikis, increased migratory capacity, and loss of contact growth inhibition in endothelial cells.
Ant Murphy   +9 more
wiley   +1 more source

The Ca2+-gated channel TMEM16A amplifies capillary pericyte contraction and reduces cerebral blood flow after ischemia

open access: yesThe Journal of Clinical Investigation, 2022
Pericyte-mediated capillary constriction decreases cerebral blood flow in stroke after an occluded artery is unblocked. The determinants of pericyte tone are poorly understood.
Nils Korte   +9 more
doaj   +1 more source

ADAMTS proteases in vascular biology

open access: yesMatrix Biology, 2015
ADAMTS (a disintegrin and metalloprotease with thrombospondin motifs) proteases comprise the most recently discovered branch of the extracellular metalloenzymes. Research during the last 15years, uncovered their association with a variety of physiological and pathological processes including blood coagulation, tissue repair, fertility, arthritis and ...
Rodríguez-Manzaneque, Juan Carlos   +3 more
openaire   +4 more sources

Home - About - Disclaimer - Privacy