Results 31 to 40 of about 2,444,251 (292)

Nuclear Factor kappa B-Mediated Transactivation of Telomerase Prevents Intimal Smooth Muscle Cell From Replicative Senescence During Vascular Repair

, 2010
Objective-To gain insights into mechanisms by which intimal hyperplasia interferes with the repair process by investigating expression and function of the catalytic telomerase reverse transcriptase (TERT) subunit after vascular injury.
Maria E. Johansson, Jingyi Ren, De-xiu Bu, F. Brad Johnson, Kristina Edfeldt, Johnson, F. Brad, Ren, Jingyi, Xu, Da-wei, Edfeldt, Kristina, Zhong-qun Yan, Johansson, Maria E., Johnson, FB, Johansson, ME, Yan, Z-Q, Ren, J, Bu, D-X, Da-wei Xu, Yan, Zhong-qun, Xu, D-W, Bu, De-xiu, Edfeldt, K,   +20 more
core   +1 more source

Heparinase selectively sheds heparan sulphate from the endothelial glycocalyx [PDF]

, 2008
A healthy vascular endothelium is coated by the endothelial glycocalyx. Its main constituents are transmembrane syndecans and bound heparan sulphates. This structure maintains the physiological endothelial permeability barrier and prevents leukocyte and ...
Rehm, Markus, Welsch, Ulrich, Jacob, Matthias, Chappell, Daniel, Conzen, Peter, Becker, Bernhard F., Stoeckelhuber, Mechthild   +6 more
core   +1 more source

The ESC Textbook of Vascular Biology [PDF]

European Heart Journal, 2017
Atherosclerosis continues to be the most significant pathology giving rise to cardiovascular disease worldwide. Vascular biology forms the basic armamentarium to address the underlying mechanisms.
openaire   +4 more sources

Progress in Stem Cell Biology and Medical Applications Stem Cells in Vascular, Muscular and Cardiac Tissues

, 2009
Progress in Stem Cell Biology and Medical Applications Stem Cells in Vascular, Muscular and Cardiac ...
Y. Torrente
core   +2 more sources

Cilia proteins are biomarkers of altered flow in the vasculature

JCI Insight, 2022
Cilia, microtubule-based organelles that project from the apical luminal surface of endothelial cells (ECs), are widely regarded as low-flow sensors. Previous reports suggest that upon high shear stress, cilia on the EC surface are lost, and more recent ...
Ankan Gupta, Karthikeyan Thirugnanam, Madhan Thamilarasan, Ashraf M. Mohieldin, Hadeel T. Zedan, Shubhangi Prabhudesai, Meghan R. Griffin, Andrew D. Spearman, Amy Pan, Sean P. Palecek, Huseyin C. Yalcin, Surya M. Nauli, Kevin R. Rarick, Rahima Zennadi, Ramani Ramchandran   +14 more
doaj   +1 more source

Neuropilin-1 deficiency in vascular smooth muscle cells is associated with hereditary hemorrhagic telangiectasia arteriovenous malformations

JCI Insight, 2022
Patients with hereditary hemorrhagic telangiectasia (HHT) have arteriovenous malformations (AVMs) with genetic mutations involving the activin-A receptor like type 1 (ACVRL1 or ALK1) and endoglin (ENG). Recent studies have shown that Neuropilin-1 (NRP-1)
Sreenivasulu Kilari, Ying Wang, Avishek Singh, Rondell P. Graham, Vivek Iyer, Scott M. Thompson, Michael S. Torbenson, Debabrata Mukhopadhyay, Sanjay Misra   +8 more
doaj   +1 more source

Vascular biology of the biliary epithelium [PDF]

Journal of Gastroenterology and Hepatology, 2013
AbstractgraphicCholangiocytes are involved in a variety of processes essential for liver pathophysiology. To meet their demanding metabolic and functional needs, bile ducts are nourished by their own arterial supply, the peribiliary plexus. This capillary network originates from the hepatic artery and is strictly arranged around the intrahepatic bile ...
Morell CM, FABRIS, LUCA, Strazzabosco M.
openaire   +4 more sources

NADPH oxidase, NOX1, mediates vascular injury in ischemic retinopathy [PDF]

, 2014
<b>Aims:</b> Ischemic retinal diseases such as retinopathy of prematurity are major causes of blindness due to damage to the retinal microvasculature.
Jandeleit-Dahm, Karin A., Agrotis, Alex, Wingler, Kirstin, Rana, Indrajeetsinh, Schmidt, Harald H. H. W., Miller, Antonia G., Szyndralewiez, Cédric, Schmidt, Harald H.H.W., Armani, Roksana, Deliyanti, Devy, Cooper, Mark E., Touyz, Rhian M., Wilkinson-Berka, Jennifer L.   +12 more
core   +2 more sources

Platelet olfactory receptor activation limits platelet reactivity and growth of aortic aneurysms

The Journal of Clinical Investigation, 2022
As blood transitions from steady laminar flow (S-flow) in healthy arteries to disturbed flow (D-flow) in aneurysmal arteries, platelets are subjected to external forces.
Craig N. Morrell, Doran Mix, Anu Aggarwal, Rohan Bhandari, Matthew Godwin, Phillip Owens III, Sean P. Lyden, Adam Doyle, Krystin Krauel, Matthew T. Rondina, Amy Mohan, Charles J. Lowenstein, Sharon Shim, Shaun Stauffer, Vara Prasad Josyula, Sara K. Ture, David I. Yule, Larry E. Wagner III, John M. Ashton, Ayman Elbadawi, Scott J. Cameron   +20 more
doaj   +1 more source

European Standard Clinical Practice Guideline and EXPeRT Recommendations for the Diagnosis and Management of Gastroenteropancreatic Neuroendocrine Neoplasms in Children and Adolescents

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Pediatric gastroenteropancreatic neuroendocrine neoplasms (GEP‐NENs) are extremely rare and clinically heterogeneous. Management has largely been extrapolated from adult practice. This European Standard Clinical Practice Guideline (ESCP), developed by the EXPeRT network in collaboration with adult NEN experts, provides (adult) evidence ...
Michaela Kuhlen, Calogero Virgone, Antje Redlich, Michael Abele, Ricardo Lopez‐Almaraz, Tal Ben‐Ami, Ewa Bien, Gianni Bisogno, Maja Mazic Cesen, Andrea Ferrari, Malgorzata A. Krawczyk, Yves Reguerre, Dominik T. Schneider, Ines B. Brecht, Charlotte Rigaud, Bilgehan Yalcin, Rainer Claus, Christian Vokuhl, Constantin Lapa, Jörg Fuchs, Segolene Hescot, Thomas Walter, Julien Hadoux, Daniel Orbach   +23 more
wiley   +1 more source